Evidence map›Paper›PMID 28393576›Full record

Observational studyLeukemia & lymphoma2017

Analysis of anticoagulation strategies for venous thromboembolism during severe thrombocytopenia in patients with hematologic malignancies: a retrospective cohort.

Damon E Houghton, Nigel S Key, Neil A Zakai, Jeffrey P Laux, Thomas C Shea, Stephan Moll

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Leukemia & lymphoma, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Anticoagulant therapy in patients with cancer and thrombocytopenia.Journal of thrombosis and thrombolysis · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Cancer-associated thrombosis in hematologic malignancies.International journal of hematology · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Review
  13. Article
  14. Article
  15. Incidence of Upper Extremity Deep Vein Thrombosis in Acute Leukemia and Effect on Mortality.TH open : companion journal to thrombosis and haemostasis · 2020
    Article
  16. Observational
  17. Review
  18. Review
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Damon E Houghtona Department of Medicine, Division of Hematology/Oncology , University of North Carolina , Chapel Hill , NC , USA.
Nigel S Keya Department of Medicine, Division of Hematology/Oncology , University of North Carolina , Chapel Hill , NC , USA.
Neil A Zakaib Departments of Medicine and Pathology , University of Vermont , Burlington , VT , USA.
Jeffrey P Lauxc University of North Carolina, The North Carolina Translational and Clinical Sciences (NC TraCS) Institute , Chapel Hill , NC , USA.
Thomas C Sheaa Department of Medicine, Division of Hematology/Oncology , University of North Carolina , Chapel Hill , NC , USA.
Stephan Molla Department of Medicine, Division of Hematology/Oncology , University of North Carolina , Chapel Hill , NC , USA.
University of North Carolina at Chapel Hill · USUniversity of Vermont · US

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)UL1TR001111 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$43.9M
Research Training in Hematology at UNC Chapel HillT32HL007149 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Nigel S. Key · 1985 to 2026
$8.6M
NCATS NIH HHS UL1 TR001111NCATS NIH HHS UL1 TR002489NHLBI NIH HHS T32 HL007149
6 · The paper itself

Abstract

The safety and efficacy of anticoagulation for venous thromboembolism (VTE) at times of severe thrombocytopenia is unclear. In this retrospective study, we evaluated patients with hematologic malignancy and either (1) acute or chronic VTE on anticoagulation before platelet count dropped below 50 × 10

Indexed as

AdultAgedAnticoagulantsBlood CoagulationFemaleHematologic NeoplasmsHemorrhageHumansMaleMiddle AgedPlatelet CountRetrospective StudiesThrombocytopeniaVenous ThromboembolismAnticoagulantsAnticoagulationhematologic malignancieshemorrhagethrombocytopeniavenous thromboembolism

Identifiers

PMID28393576
PMCPMC8211440
OpenAlexW2607302953

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.