Evidence map›Paper›PMID 28393524›Full record

ArticleJournal of agricultural and food chemistry2017

Changes in Caprine Milk Oligosaccharides at Different Lactation Stages Analyzed by High Performance Liquid Chromatography Coupled to Mass Spectrometry.

Andrea Martín-Ortiz, Daniela Barile, Jaime Salcedo, F Javier Moreno, Alfonso Clemente, Ana I Ruiz-Matute, María L Sanz

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of agricultural and food chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Determination of aflatoxin MMycotoxin research · 2024
    Article
  5. Biological Relevance of Goat Milk Oligosaccharides to Infant Health.Journal of agricultural and food chemistry · 2023
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Targeted LC-ESI-MSAnalytical and bioanalytical chemistry · 2020
    Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Andrea Martín-OrtizInstituto de Química Orgánica General (CSIC) , Juan de la Cierva, 3, 28006 Madrid, Spain.
Daniela BarileDepartment of Food Science and Technology, University of California Davis , One Shields Avenue, Davis, California 95616, United States.ORCID http://orcid.org/0000-0002-3889-1596
Jaime SalcedoDepartment of Food Science and Technology, University of California Davis , One Shields Avenue, Davis, California 95616, United States.
F Javier MorenoInstituto de Investigación en Ciencias de la Alimentación, CIAL (CSIC-UAM), C/Nicolás Cabrera, 9, Campus de Cantoblanco - Universidad Autónoma de Madrid , 28049 Madrid, Spain.
Alfonso ClementeEstación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas (CSIC) , Profesor Albareda 1, 18008 Granada, Spain.
Ana I Ruiz-MatuteInstituto de Química Orgánica General (CSIC) , Juan de la Cierva, 3, 28006 Madrid, Spain.
María L SanzInstituto de Química Orgánica General (CSIC) , Juan de la Cierva, 3, 28006 Madrid, Spain.
Instituto de Química Orgánica General · ESUniversity of California, Davis · USConsejo Superior de Investigaciones Científicas · ESInstituto de Investigación en Ciencias de la Alimentación · ES

Funding

Activation of probiotic bifidobacteria by milk glyansR01AT008759 · NCCIH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GERMAN, BRUCE, LEBRILLA, CARLITO B · 2014 to 2018
$4.2M
Mechanism of Activation of Probiotic Bifidobacteria by Prebiotic Milk GlycansR01AT007079 · NCCIH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GERMAN, BRUCE, LEBRILLA, CARLITO B · 2012 to 2016
$2.2M
Activation of Host-Probiotic Communication by Prebiotic Milk OligosaccharidesR21AT006180 · NCCIH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MILLS, DAVID ANDREW, RAYBOULD, HELEN E · 2011 to 2012
$421k
NCCIH NIH HHS R01 AT007079NCCIH NIH HHS R01 AT008759NCCIH NIH HHS R21 AT006180
6 · The paper itself

Abstract

Changes of the abundance of caprine milk oligosaccharides (CMO) at different lactation stages have been evaluated by hydrophilic interaction liquid chromatography coupled to mass spectrometry (HILIC-Q MS) and nanoflow liquid chromatography-quadrupole-time-of-flight mass spectrometry (nano-LC-Chip-QTOF MS). Eight major oligosaccharides (OS) were quantified at different lactation stages by HILIC-Q MS, while the use of nano-LC-Chip-QToF MS allowed expanding the study to forty-nine different OS by monitoring neutral non- and fucosylated species, as well as acidic species containing not only N-acetyl-neuraminic acid or N-glycolyl-neuraminic acid residues but also the combination of both sialic acids. Overall, the most abundant OS decreased with lactation time, whereas different trends were observed for minor OS. 6'-Sialyl-lactose was the most abundant acidic OS while galactosyl-lactose isomers were identified as the most abundant neutral OS. This is the first time that a comprehensive study regarding the changes of the abundance of CMO, both neutral and acidic, at different lactation stages is carried out.

Indexed as

AnimalsChromatography, High Pressure LiquidFemaleGoatsIsomerismLactationMass SpectrometryMilkMolecular StructureOligosaccharidesOligosaccharidesgoat milk oligosaccharideshydrophilic interaction liquid chromatographylactation stagesnanoflow liquid chromatography−quadrupole-time-of-flight mass spectrometry

Identifiers

PMID28393524
PMCPMC5557284
OpenAlexW2606499362

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.