Evidence map›Paper›PMID 28393324›Full record

ArticleJournal of abnormal child psychology2018

Maternal Prenatal Stress and Other Developmental Risk Factors for Adolescent Depression: Spotlight on Sex Differences.

Seth D Maxwell, Anna M Fineberg, Deborah A Drabick, Shannon K Murphy, Lauren M Ellman

Abstract read
In one paragraph

Article in Journal of abnormal child psychology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Familial clustering of birth risk for adverse childhood outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Seth D MaxwellDepartment of Psychology, Temple University, 1701 N. 13th Street, Philadelphia, PA, 19122, USA.
Anna M FinebergDepartment of Psychology, Temple University, 1701 N. 13th Street, Philadelphia, PA, 19122, USA.
Deborah A DrabickDepartment of Psychology, Temple University, 1701 N. 13th Street, Philadelphia, PA, 19122, USA.
Shannon K MurphyDepartment of Psychology, Temple University, 1701 N. 13th Street, Philadelphia, PA, 19122, USA.
Lauren M EllmanDepartment of Psychology, Temple University, 1701 N. 13th Street, Philadelphia, PA, 19122, USA. ellman@temple.edu.

Funding

Training in Schizophrenia and Psychotic Disorders: From Animal Models to PatientsT32MH018870 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Guillermo Horga, Christoph Kellendonk · 1988 to 2026
$9.8M
Fetal exposure to maternal stress and inflammation: Effects on neurodevelopmentR01MH096478 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ELLMAN, LAUREN M · 2012 to 2016
$2.1M
NICHD NIH HHS HHSN275201100020CNIMH NIH HHS R01 MH096478NIMH NIH HHS T32 MH018870
6 · The paper itself

Abstract

Maternal stress during pregnancy has been linked to premorbid abnormalities associated with depression (e.g., difficult temperament, cognitive deficits) in offspring. However, few studies have looked across developmental periods to examine maternal stress during pregnancy and offspring depression during adolescence and whether these associations differ by sex. The current study used data from 1711 mother-offspring dyads (offspring sex: 49.8% male) in a longitudinal birth cohort study. Maternal narratives collected during pregnancy were qualitatively coded for stress-related themes by independent raters. Latent class analysis (LCA) identified distinct subgroups of offspring based on exposure to maternal prenatal stress and other developmental factors from the prenatal, childhood, and adolescent periods that have been associated with depression and/or maternal prenatal stress. LCA identified subgroups that were compared to determine whether and to what extent they differed on adolescent depressive symptoms. LCA revealed a subgroup of "high-risk" individuals, characterized by maternal factors during pregnancy (higher ambivalence/negativity and lower positivity towards the pregnancy, higher levels of hassles, lower maternal education and higher maternal age at birth, higher pre-pregnancy BMI) and offspring developmental factors (decreased cognitive functioning during childhood and adolescence, lower perceived parental support during adolescence, and higher levels of maternal depression during adolescence). High-risk females exhibited elevated conduct symptoms and higher birth order, while high-risk males exhibited decreased internalizing symptoms and lower birth order. Both high-risk males and females reported elevated depressive symptoms during adolescence relative to their "low-risk" counterparts.

Indexed as

Adolescent DevelopmentBirth OrderChild DevelopmentAdolescentAdultAnxietyCaliforniaChildConduct DisorderDepressionFemaleHumansLongitudinal StudiesMalePregnancyPrenatal Exposure Delayed EffectsAdolescenceDepressionDevelopmental risk factorsPrenatal stressSex differences

Identifiers

PMID28393324
PMCPMC5828524

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.