Evidence map›Paper›PMID 28393135›Full record

ArticleACS omega2017

Identification of 4-(3-Pyridyl)-4-oxobutyl-2'-deoxycytidine Adducts Formed in the Reaction of DNA with 4-(Acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone: A Chemically Activated Form of Tobacco-Specific Carcinogens.

Anna K Michel, Adam T Zarth, Pramod Upadhyaya, Stephen S Hecht

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. A Novel Adductomics Workflow IncorporatingEnvironmental science & technology · 2024
    Article
  2. Metabolism and DNA Adduct Formation of Tobacco-SpecificInternational journal of molecular sciences · 2022
    Review
  3. Review
  4. Article
  5. Article
  6. Chemical Analysis of DNA Damage.Analytical chemistry · 2018
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anna K MichelMasonic Cancer Center, University of Minnesota , 2231 6th Street SE, Room 2-148 CCRB, Minneapolis, Minnesota 55455, United States.
Adam T ZarthMasonic Cancer Center, University of Minnesota , 2231 6th Street SE, Room 2-148 CCRB, Minneapolis, Minnesota 55455, United States.
Pramod UpadhyayaMasonic Cancer Center, University of Minnesota , 2231 6th Street SE, Room 2-148 CCRB, Minneapolis, Minnesota 55455, United States.
Stephen S HechtMasonic Cancer Center, University of Minnesota , 2231 6th Street SE, Room 2-148 CCRB, Minneapolis, Minnesota 55455, United States.
University of Minnesota · US

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Douglas Yee · 1998 to 2026
$100.4M
TRAINING-PULMONARY CELL &MOLECULAR BIOLOGY &PHYSIOLOGYT32HL007741 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI DUDLEY, R. ADAMS, INGBAR, DAVID H · 1994 to 2023
$13.9M
METABOLISM OF CARCINOGENIC TOBACCO SPECIFIC NITROSAMINESR01CA081301 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI STEPHEN S HECHT · 1999 to 2026
$7.1M
NCI NIH HHS P30 CA077598NCI NIH HHS R01 CA081301NHLBI NIH HHS T32 HL007741
6 · The paper itself

Abstract

Metabolic activation of the carcinogenic tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK,

Identifiers

PMID28393135
PMCPMC5377278
OpenAlexW2601587630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.