Evidence map›Paper›PMID 28393112›Full record

ArticleJournal of nature and science2017

Chromatin replication: TRANSmitting the histone code.

Han-Wen Chang, Vasily M Studitsky

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of nature and science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Structure and function of the histone chaperone FACT - Resolving FACTual issues.Biochimica et biophysica acta. Gene regulatory mechanisms · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Han-Wen ChangFox Chase Cancer Center, Philadelphia, PA 19111, USA.
Vasily M StuditskyFox Chase Cancer Center, Philadelphia, PA 19111, USA; Biology Faculty, Lomonosov Moscow State University; Moscow, Russia.

Funding

Mechanism Transcript Elongation in ChromatinR01GM058650 · NIGMS · WAYNE STATE UNIVERSITY · PI STUDITSKY, VASILY M · 1999 to 2015
$4.7M
Mechanism of yFACT Action during Chromatin TranscriptionR01GM119398 · NIGMS · RESEARCH INST OF FOX CHASE CAN CTR · PI STILLMAN, DAVID J, STUDITSKY, VASILY M · 2017 to 2020
$1.3M
NIGMS NIH HHS R01 GM058650NIGMS NIH HHS R01 GM119398
6 · The paper itself

Abstract

Efficient overcoming of the nucleosomal barrier and accurate maintenance of associated histone marks during chromatin replication are essential for normal functioning of the cell. Recent studies revealed new protein factors and histone modifications contributing to overcoming the nucleosomal barrier, and suggested an important role for DNA looping in survival of the original histones during replication. These studies suggest new possible mechanisms for transmitting the histone code to next generations of cells.

Indexed as

Chromatinhistonesnucleosomereplicationsegregation

Identifiers

PMID28393112
PMCPMC5384335

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.