Evidence map›Paper›PMID 28393080›Full record

ArticleJournal of immunology research2017

Gene Expression Profiles of Human Phosphotyrosine Phosphatases Consequent to Th1 Polarisation and Effector Function.

Patricia Castro-Sánchez, Rocio Ramirez-Munoz, Pedro Roda-Navarro

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Regulation of CD4Frontiers in immunology · 2019
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Patricia Castro-SánchezDepartment of Microbiology I (Immunology), School of Medicine, Complutense University and "12 de Octubre" Health Research Institute, Madrid, Spain.
Rocio Ramirez-MunozDepartment of Microbiology I (Immunology), School of Medicine, Complutense University and "12 de Octubre" Health Research Institute, Madrid, Spain.
Pedro Roda-NavarroDepartment of Microbiology I (Immunology), School of Medicine, Complutense University and "12 de Octubre" Health Research Institute, Madrid, Spain.ORCID 0000-0003-3799-8823

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphotyrosine phosphatases (PTPs) constitute a complex family of enzymes that control the balance of intracellular phosphorylation levels to allow cell responses while avoiding the development of diseases. Despite the relevance of CD4 T cell polarisation and effector function in human autoimmune diseases, the expression profile of PTPs during T helper polarisation and restimulation at inflammatory sites has not been assessed. Here, a systematic analysis of the expression profile of PTPs has been carried out during Th1-polarising conditions and upon PKC activation and intracellular raise of Ca

Indexed as

TranscriptomeAutoimmune DiseasesCalciumCD4-Positive T-LymphocytesCell DifferentiationHumansLymphocyte ActivationProtein Tyrosine PhosphatasesSignal TransductionTh1 CellsCalciumProtein Tyrosine Phosphatases

Identifiers

PMID28393080
PMCPMC5368384
OpenAlexW2599511027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.