Evidence map›Paper›PMID 28393054›Full record

ArticleIranian journal of otorhinolaryngology2017

Otitis Media with Effusion in Children and the Impact of Risk Factors on Serum Cytokine Levels.

Saba Arshi, Fatemeh Dehghani Firouzabadi, Babak Ghalehbaghi, Ali Dehghani Firouzabadi, Farhad Jalali, Mehdi Shekarabi, Reza Sirous, Mohammad Dehghani Firouzabadi

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In one paragraph

Article in Iranian journal of otorhinolaryngology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Blood biomarker-based risk factors and predictive model for middle ear cholesterol granuloma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Saba ArshiDepartment of Allergy and Clinical Immunology, Iran University of Medical Sciences, Tehran, Iran.
Fatemeh Dehghani FirouzabadiENT and Head and Neck Research Center and Department   , Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences,Tehran,Iran.
Babak GhalehbaghiENT and Head and Neck Research Center and Department   , Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences,Tehran,Iran.
Ali Dehghani FirouzabadiDepartment of Health, Epidemiologist, Mississippi State, United States.
Farhad JalaliDepartment of Allergy and Clinical Immunology, Iran University of Medical Sciences, Tehran, Iran.
Mehdi ShekarabiDepartment of Allergy and Clinical Immunology, Iran University of Medical Sciences, Tehran, Iran.
Reza SirousDepartment of Radiology, University of Mississippi Medical Center, Mississippi State, United States.
Mohammad Dehghani FirouzabadiENT and Head and Neck Research Center and Department   , Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences,Tehran,Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo evaluate the role of allergic-type and infectious-type cytokines in children with chronic otitis media with effusion (OME). MATERIALS AND

methodsWe investigated serum levels of interleukins (IL)-4, IL-5, and IL-13, along with interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α), by enzyme-linked immunosorbent assay (ELISA) in 35 children with OME and 28 healthy controls.

resultsChildren with OME had significantly higher levels of IL-5 in comparison with the control group, ranging from 1 pg/ml in cases to 0.04 pg/ml in controls (P=0.009). However, after adjusting for confounding variables, there was no significant difference in serum levels of IL-13, IL-4, IFN-γ, or TNF-α between the two groups (P=0.287, P=0.627, P=0.793, and P=0.217, respectively).

conclusionsThe findings of this study suggest that in comparison with the control group, serum IL-5 levels were elevated in OME cases.

Indexed as

Inflammatory cytokinesInterleukinsOtitis media with effusionPediatrics

Identifiers

PMID28393054
PMCPMC5380392

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