Evidence map›Paper›PMID 28393028›Full record

ArticleInternational journal of ophthalmology2017

Analysis of corneal morphologic and pathologic changes in early-stage congenital aniridic keratopathy.

Juan Du, Rong-Qiang Liu, Lei Ye, Zhi-Hui Li, Feng-Tu Zhao, Nan Jiang, Lin-Hong Ye, Yi Shao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Juan DuDepartment of Ophthalmology, the First People's Hospital of Shunde, Nanfang Medical University, Foshan 528300,Guangdong Province, China.
Rong-Qiang LiuDepartment of ophthalmology, the First Affiliated Hospital of Nanchang University, Jiangxi Province Clinical Ophthalmology Institute, Nanchang 330006, Jiangxi Province, China; Postgraduate College, the Third hospital Affiliated of Sun Yat-sen University, Guangzhou 510000, Guangdong Province, China.
Lei YeDepartment of ophthalmology, the First Affiliated Hospital of Nanchang University, Jiangxi Province Clinical Ophthalmology Institute, Nanchang 330006, Jiangxi Province, China.
Zhi-Hui LiDepartment of Ophthalmology, the First People's Hospital of Shunde, Nanfang Medical University, Foshan 528300,Guangdong Province, China.
Feng-Tu ZhaoDepartment of Ophthalmology, the First People's Hospital of Shunde, Nanfang Medical University, Foshan 528300,Guangdong Province, China.
Nan JiangDepartment of ophthalmology, the First Affiliated Hospital of Nanchang University, Jiangxi Province Clinical Ophthalmology Institute, Nanchang 330006, Jiangxi Province, China.
Lin-Hong YeDepartment of ophthalmology, the First Affiliated Hospital of Nanchang University, Jiangxi Province Clinical Ophthalmology Institute, Nanchang 330006, Jiangxi Province, China.
Yi ShaoDepartment of ophthalmology, the First Affiliated Hospital of Nanchang University, Jiangxi Province Clinical Ophthalmology Institute, Nanchang 330006, Jiangxi Province, China.
First Affiliated Hospital of Nanchang University · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine typical corneal changes of congenital aniridic keratopathy (CAK) using corneal topography and confocal systems, and to identify characteristics that might assist in early diagnosis.

methodsPatients with CAK and healthy control subjects underwent detailed ophthalmic examinations including axial length, corneal thickness, tear film condition, corneal topography, and laser-scanning

resultsIn early stage aniridic keratopathy, Schirmer I test (SIT), break-up time (BUT), mean keratometry (mean K) and simulated keratometry (sim K) were reduced relative to controls (

conclusionThese changes in corneal morphology in borderline situations can be useful to confirm the diagnosis of CAK.

Indexed as

aniridic keratopathyconfocal microscopycorneal topography

Identifiers

PMID28393028
PMCPMC5360772
OpenAlexW2615302477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.