Evidence map›Paper›PMID 28392959›Full record

ArticleJournal of pharmacopuncture2017

Restricted Blood Flow Exercise in Sedentary, Overweight African-American Females May Increase Muscle Strength and Decrease Endothelial Function and Vascular Autoregulation.

Vernon Bond, Bryan Heath Curry, Krishna Kumar, Sudhakar Pemminati, Vasavi Rakesh Gorantla, Kishan Kadur, Richard Mark Millis

Open access · diamondAbstract read
In one paragraph

Article in Journal of pharmacopuncture, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Current Trends in Blood Flow Restriction.Frontiers in physiology · 2022
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Vernon BondDepartment of Recreation, Human Performance & Leisure Studies and Exercise Science & Human Nutrition Laboratory, Howard University Cancer Centre, Washington DC, United States of America.
Bryan Heath CurryDepartment of Medicine, Division of Cardiology, Howard College of Medicine & Howard University Hospital, Washington DC, United States of America.
Krishna KumarDepartment of Pharmaceutical Sciences, Howard University Hospital, Washington DC, United States of America.
Sudhakar PemminatiDepartment of Medical Pharmacology, AUA College of Medicine & Manipal University, Antigua and Barbuda.
Vasavi Rakesh GorantlaDepartment of Behavioural Sciences and Neuroscience, AUA College of Medicine, Antigua and Barbuda.
Kishan KadurDepartment of Medical Physiology, AUA College of Medicine, Antigua and Barbuda.
Richard Mark MillisDepartment of Medical Physiology, AUA College of Medicine, Antigua and Barbuda.
Howard University · US

Funding

PROTEOMICS CORE FACILITYG12MD007597 · NIMHD · HOWARD UNIVERSITY · PI SOUTHERLAND, WILLIAM M. · 2012 to 2018
$14.8M
NIMHD NIH HHS G12 MD007597
6 · The paper itself

Abstract

objectivesExercise with partially restricted blood flow is a low-load, low-intensity resistance training regimen which may have the potential to increase muscle strength in the obese, elderly and frail who are unable to do high-load training. Restricted blood flow exercise has also been shown to affect blood vessel function variably and can, therefore, contribute to blood vessel dysfunction. This pilot study tests the hypothesis that unilateral resistance training of the leg extensors with partially restricted blood flow increases muscle strength and decreases vascular autoregulation.

methodsThe subjects were nine normotensive, overweight, young adult African-Americans with low cardiorespiratory fitness who underwent unilateral training of the quadriceps' femoris muscles with partially restricted blood flow at 30% of the 1-repetition maximum (1-RM) load for 3 weeks. The 1-RM load and post-occlusion blood flow to the lower leg (calf) were measured during reactive hyperemia.

resultsThe 1-RM load increased in the trained legs from 77 ± 3 to 84 ± 4 kg (

conclusionThese results demonstrate that restricted blood flow exercise, which results in significant gains in muscle strength, may produce decrements in endothelial dysfunction and vascular autoregulation. Future studies should determine whether pharmacopuncture plays a role in treatments for such blood vessel dysfunction.

Indexed as

Kaatsuquadriceps femorisresistance trainingskeletal muscle

Identifiers

PMID28392959
PMCPMC5374335
OpenAlexW2599943927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.