Evidence map›Paper›PMID 28392861›Full record

ArticleJournal of clinical medicine research2017

Reported Exercise-Related Respiratory Symptoms and Exercise-Induced Bronchoconstriction in Asthmatic Children.

Demet Inci, Refoel Guggenheim, Derya Ufuk Altintas, Johannes H Wildhaber, Alexander Moeller

Abstract read
In one paragraph

Article in Journal of clinical medicine research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Demet InciDivision of Respiratory Medicine, University Children's Hospital Zurich, Steinwiesstrasse 75, 8032 Zurich, Switzerland.
Refoel GuggenheimDivision of Respiratory Medicine, University Children's Hospital Zurich, Steinwiesstrasse 75, 8032 Zurich, Switzerland.
Derya Ufuk AltintasDivision of Paediatric Allergy and Immunology, Faculty of Medicine, University of Cukurova, 01330 Balcali, Saricam/Adana, Turkey.
Johannes H WildhaberDepartment of Paediatrics, Cantonal Hospital Fribourg, HFR 1708 Freiburg, Switzerland.
Alexander MoellerDivision of Respiratory Medicine, University Children's Hospital Zurich, Steinwiesstrasse 75, 8032 Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnlimited physical activity is one of the key issues of asthma control and management. We investigated how reliable reported exercise-related respiratory symptoms (ERRS) are in predicting exercise-induced bronchoconstriction (EIB) in asthmatic children.

methodsIn this prospective study, 179 asthmatic children aged 7 - 15 years were asked for specific questions on respiratory symptoms related to exercise and allocated into two groups according to whether they complained about symptoms. Group I (n = 134) consisted of children answering "yes" to one or more of the questions and group II (n = 45) consisted of children answering "no" to all of the questions.

resultsSixty-four of 179 children showed a positive exercise challenge test (ECT). There was no difference in the frequency of a positive test between children in group I (n = 48) and group II (n = 12) (P = 0.47). The sensitivity of a positive report for ERRS to predict a positive ECT was only 37%, with a specificity of 0.72.

conclusionAccording to current guidelines, the report or lack of ERRS has direct consequences on treatment decisions. However, the history of ERRS did not predict EIB and one-third of asthmatic children without complaints of ERRS developed EIB during the ECT. This raises the question of the need for objective measures of bronchial hyperresponsiveness (BHR) in pediatric asthma management.

Indexed as

ChildrenExercise challenge testExercise-induced asthmaExercise-induced bronchoconstrictionRespiratory symptoms

Identifiers

PMID28392861
PMCPMC5380174

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