Evidence map›Paper›PMID 28392751›Full record

ArticleClinical and molecular allergy : CMA2017

Effects of specific allergen immunotherapy on biological markers and clinical parameters in asthmatic children: a controlled-real life study.

I Djuric-Filipovic, Marco Caminati, D Filipovic, C Salvottini, Z Zivkovic

Open access · goldAbstract read
In one paragraph

Article in Clinical and molecular allergy : CMA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Through the Looking Glass:Applied in vitro toxicology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

I Djuric-FilipovicFaculty of Medical Science, University of Kragujevac, Svetozara Markovica 64, 34000 Kragujevac, Serbia.
Marco CaminatiAllergy Unit and Asthma Center, Verona University and General Hospital, Piazzale Stefani 1, 37126 Verona, Italy.
D FilipovicInstitution for Emergency Medical Care, Bulevar Franša Depera 5, 11000 Belgrade, Serbia.
C SalvottiniDepartment of Internal Medicine and Therapeutics, University of Pavia, Strada Nuova 65, Pavia, Italy.
Z ZivkovicChildren's Hospital for Lung Diseases and Tuberculosis, Medical Center "Dr. Dragiša Mišović", Belgrade, Pilota Mihajla Tepica 1, 11000 Belgrade, Serbia.
University Hospital Center Dr Dragiša Mišović · RSUniversity of Kragujevac · RSUniversity of Pavia · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAllergen-specific immunotherapy (AIT) is the only treatment able to change the natural course of allergic diseases. We aimed at investigating the clinical efficacy of SLITOR (Serbian registered vaccine for sublingual allergen specific immunotherapy).

methods7-18 years old children with allergic asthma and rhinitis were enrolled and addressed to the active (AIT plus pharmacological treatment) or control (standard pharmacological treatment only) group. Clinical and medications scores, lung function and exhaled FeNO were measured at baseline and at every follow-up.

resultsThere was a significant improvement in both nasal and asthma symptom scores as well as in medication score in SLIT group. SLIT showed an important influence on lung function and airway inflammation.

conclusionsOur data showed that SLITOR was effective not only in terms of patient reported outcomes but an improvement of pulmonary function and decrease of lower airway inflammation were also observed.

Indexed as

Allergen specific immunotherapyAsthmaChildhoodexhaled NO

Identifiers

PMID28392751
PMCPMC5376712
OpenAlexW2604811888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.