ArticleJournal of pain research2017
Dynamic abnormalities of spontaneous brain activity in women with primary dysmenorrhea.
Article in Journal of pain research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Dysmenorrhea and psychological distress: a meta-analysis.Archives of women's mental health · 2023Pooled it
- Neural correlates of co-occurring pain and depression: an activation-likelihood estimation (ALE) meta-analysis and systematic review.Translational psychiatry · 2022Pooled it
- The medial temporal lobe in nociception: a meta-analytic and functional connectivity study.Pain · 2019Pooled it
- Unaltered intrinsic functional brain architecture in young women with primary dysmenorrhea.Scientific reports · 2018Trial
- Traditional Chinese Manual Therapy (Tuina) relieves neuropathic pain by regulating neuroplasticity: A resting-state functional magnetic resonance imaging study.IBRO neuroscience reports · 2026Article
- Exercise intervention for rumination: from neural mechanisms to clinical applications.Frontiers in psychology · 2026Review
- Effect of acupuncture on brain activity in patients with decreasing ovarian reserve: a resting-state functional magnetic resonance imaging study.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2025Article
- Abnormal amplitude of low-frequency fluctuations and functional connectivity in patients with primary dysmenorrhea.Frontiers in integrative neuroscience · 2025Article
- Article
- Revealing the mechanism of central pain hypersensitivity in primary dysmenorrhea: evidence from neuroimaging.Quantitative imaging in medicine and surgery · 2024Article
- Adaptive neuroplasticity in the default mode network contributing to absence of central sensitization in primary dysmenorrhea.Frontiers in neuroscience · 2023Article
- Insight into Dysmenorrhea Research from 1992 to 2022: A Bibliometric Analysis.Journal of pain research · 2023Review
- Differences in the distribution of triggers among resting state networks in patients with juvenile myoclonic epilepsy explained by network analysis.Frontiers in neuroscience · 2023Article
- Altered brain activities in mesocorticolimbic pathway in primary dysmenorrhea patients of long-term menstrual pain.Frontiers in neuroscience · 2023Article
- The Effect of Long-Term Menstrual Pain on Large-Scale Brain Network in Primary Dysmenorrhea Patients.Journal of pain research · 2022Article
- Not Only in Sensorimotor Network: Local and Distant Cerebral Inherent Activity of Chronic Ankle Instability-A Resting-State fMRI Study.Frontiers in neuroscience · 2022Article
- Analgesia Effect of Verum and Sham Acupuncture Treatments in Primary Dysmenorrhea: A MRI Pilot Study.Journal of personalized medicine · 2021Article
- Assessment of normalized cerebral blood flow and its connectivity with migraines without aura during interictal periods by arterial spin labeling.The journal of headache and pain · 2021Article
- Altered Posterior Cerebellar Lobule Connectivity With Perigenual Anterior Cingulate Cortex in Women With Primary Dysmenorrhea.Frontiers in neurology · 2021Article
- Immediate Analgesic Effect of Acupuncture in Patients With Primary Dysmenorrhea: A fMRI Study.Frontiers in neuroscience · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to investigate the regional spontaneous brain activity changes in primary dysmenorrhea (PD) patients in different phases of the menstrual cycle by regional homogeneity (ReHo) analysis. PATIENTS AND
methodsThirty-three PD patients and 32 healthy controls (HCs) separately received resting-state functional magnetic resonance imaging during menstrual phase and follicular phase (non-menstrual phase). Cox retrospective symptom scale (RSS), Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) were applied to assess related symptoms and emotions.
resultsThere was no significant difference between the two groups in demographic data. The PD patients obtained higher RSS score, SAS score and SDS score than HCs. Compared with HCs, the ReHo values of the PD patients were increased in left midbrain and hippocampus, right posterior cingulate cortex (PCC), insula and middle temporal cortex (MTC) and decreased in left dorsolateral prefrontal cortex and right medial prefrontal cortex (mPFC) in menstrual phase. In non-menstrual phase, enhanced ReHo values were found in bilateral S1 and precuneus, left S2 and MTC, and reduced ReHo values were observed in left mPFC and orbital frontal cortex. RSS score positively correlated with ReHo values of midbrain and negatively correlated with mPFC and PCC.
conclusionOur results suggested that PD is accompanied by dynamic regional spontaneous activity changes across the menstrual cycle, and the altered regions were involved in descending pain modulation, default mode network and sensory modulation. These abnormal activations might contribute to maintain the menstrual pain.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.