ArticleJournal of asthma and allergy2017
Factors predicting persistence of early wheezing through childhood and adolescence: a systematic review of the literature.
Article in Journal of asthma and allergy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk Factors in Preschool Children for Predicting Asthma During the Preschool Age and the Early School Age: a Systematic Review and Meta-Analysis.Current allergy and asthma reports · 2017Pooled it
- The acuity of paediatric asthma in the emergency department worsened after the COVID-19 pandemic in Alberta, Canada.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2026Article
- Incidence, viral etiology, and risk factors of wheezing in children under two years of age: findings from a low-income urban community in Dhaka, Bangladesh.BMC pulmonary medicine · 2026Article
- Asthma Hospitalizations in Children Before and After COVID-19: Insights from Northern Colombia.Clinics and practice · 2025Article
- Sensitization Patterns to Aeroallergens and Food Allergens Among Children with Atopic Asthma in Southwestern Saudi Arabia.Children (Basel, Switzerland) · 2025Article
- Adult Outcomes of Childhood Wheezing Phenotypes Are Associated with Early-Life Factors.Journal of personalized medicine · 2024Article
- Exposure to agricultural pesticides and wheezing among 5-12-year-old children in the Imperial Valley, CA, USA.Environmental epidemiology (Philadelphia, Pa.) · 2024Article
- Article
- Dysregulation of iron homeostasis in airways associated with persistent preschool wheezing.Respiratory research · 2023Article
- A pilot study exploring the association of bronchial bacterial microbiota and recurrent wheezing in infants with atopy.Frontiers in cellular and infection microbiology · 2023Article
- Persistent Asthma at School Age: Associated Factors in Preschool Children with Asthma.Children (Basel, Switzerland) · 2022Article
- The role of epigenetics in multi-generational transmission of asthma: An NIAID workshop report-based narrative review.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022Review
- Bacterial composition and colony structure of the lower respiratory tract in infants and children with recurrent wheezing: a case-control study.Italian journal of pediatrics · 2022Article
- Factors associated with resolution of childhood asthma by the age of 17: Large cohort analysis.Pediatric pulmonology · 2022Article
- Development of Sensitization to Multiple Allergen Molecules from Preschool to School Age Is Related to Asthma.International archives of allergy and immunology · 2022Article
- Transitions between alternating childhood allergy sensitization and current asthma states: A retrospective cohort analysis.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022Article
- Prevalence of infantile wheezing and eczema in a metropolitan city in Japan: A complete census survey.PloS one · 2022Article
- Prevalence and Determinants of Wheezing and Bronchodilatation in Children With Cystic Fibrosis: A Retrospective Cohort Study.Frontiers in pediatrics · 2022Article
- The impact of a digital wheeze detector on parental disease management of pre-school children suffering from wheezing-a pilot study.Pilot and feasibility studies · 2021Article
- Rhinovirus Infection and Familial Atopy Predict Persistent Asthma and Sensitisation 7 Years after a First Episode of Acute Bronchiolitis in Infancy.Children (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFor the early identification of persistent asthma symptoms among young children with recurrent wheezing, it would be helpful to identify all available studies that have identified at least one factor for predicting the persistence of early wheezing. The objective of the present study was to perform a systematic review of all studies that have identified factors that predict the persistence of symptoms among young patients with recurring wheezing.
methodsA systematic review of relevant studies was conducted through searching in MEDLINE, EMBASE, CINHAL, and SCOPUS databases up to June 2016. Studies that identified predictors of persistence of wheezing illness among young children with recurrent wheezing were retrieved. Two independent reviewers screened the literature and extracted relevant data.
resultsThe literature search returned 649 references, 619 of which were excluded due to their irrelevance. Five additional studies were identified from reference lists, and 35 studies were finally included in the review. Among all the identified predictors, the most frequently identified ones were the following: family asthma or atopy; personal history of atopic diseases; allergic sensitization early in life; and frequency, clinical pattern, or severity of wheezing/symptoms.
conclusionParental asthma (especially maternal), parental allergy, eczema, allergic rhinitis, persistent wheezing, wheeze without colds, exercise-induced wheeze, severe wheezing episodes, allergic sensitization (especially polysensitization), eosinophils (blood or eosinophil cationic protein in nasal sample), and fraction of exhaled nitric oxide were risk factors predicting persistence of early wheezing through school age. All of them are included in conventional algorithms, for example, Asthma Predictive Index and its modifications, for predicting future asthma.
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