Evidence map›Paper›PMID 28392673›Full record

ArticleCognitive and behavioral practice2017

"Life-Steps" for PrEP Adherence: Demonstration of a CBT-Based Intervention to Increase Adherence to Preexposure Prophylaxis (PrEP) Medication Among Sexual-Minority Men at High Risk for HIV Acquisition.

S Wade Taylor, Christina Psaros, David W Pantalone, Jake Tinsley, Steven A Elsesser, Kenneth H Mayer, Steven A Safren

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Cognitive and behavioral practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07385183 (CARE), which is not on this map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07385183 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

CARE: Comprehensive Assessment of Real-world Effectiveness of F/TAF in Persons Who Use Drugs (PWUD)

TypeobservationalSponsorHeather HendersonRan2026 to 2027Enrolled200ConditionsPeople Who Inject Drugs, PrEP AdherenceArmsPrEP adherence, PrEP perspectives
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 45 citations in OpenAlex.

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  2. Validation of the PrEP Use Self-Efficacy (PrEP-Use) Scale Among Sexual Minority Men.AIDS education and prevention : official publication of the International Society for AIDS Education · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

S Wade TaylorWheelock College and Fenway Health.
Christina PsarosHarvard Medical School and Massachusetts General Hospital.
David W PantaloneFenway Health and University of Massachusetts Boston.
Jake TinsleyFenway Health.
Steven A ElsesserFenway Health and Thomas Jefferson University, Sidney Kimmel Medical College.
Kenneth H MayerFenway Health and Harvard Medical School and Massachusetts General Hospital.
Steven A SafrenFenway Health, Harvard Medical School and Massachusetts General Hospital, and University of Miami.
Fenway Health · USHarvard University · USMassachusetts General Hospital · USUniversity of Massachusetts Boston · USUniversity of Miami · USWheelock College · US

Funding

Perinatal Depression, Stigma, Social Capital Utilization and PMTCT AdherenceK23MH096651 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI PSAROS, CHRISTINA · 2012 to 2016
$843k
Optimizing Antiretroviral-Based Prevention by Enhancing PrEP Adherence in MSMR34MH095584 · NIMH · FENWAY COMMUNITY HEALTH CENTER · PI MAYER, KENNETH H · 2011 to 2013
$739k
NIMH NIH HHS K23 MH096651NIMH NIH HHS R34 MH095584
6 · The paper itself

Abstract

One dramatic advance in human immunodeficiency virus (HIV) prevention efforts has been the prescription of medications typically used for HIV treatment as prophylaxis against acquiring HIV. As a preventative agent, this practice is referred to as "preexposure prophylaxis" (PrEP). The U.S. Federal Drug Administration approved daily PrEP for adults at risk for HIV who do not consistently use condoms during sex with HIV-infected or unknown-status partners. In this paper, we describe a cognitive-behavioral therapy (CBT) PrEP adherence intervention developed for use in high-risk sexual-minority men in the United States, adapted from "Life-Steps," an evidence-based CBT intervention to promote adherence to HIV treatment. Modules include creating a PrEP dosing schedule, adhering to daily PrEP, problem solving barriers to adherence, and sexual risk-reduction techniques. Supplemented with practical video vignettes, this novel intervention may help to enhance the clinical practice of health care providers in outpatient settings to increase PrEP adherence in sexual-minority men.

Indexed as

CBTHIVmedication adherenceMSMPrEP

Identifiers

PMID28392673
PMCPMC5381825
OpenAlexW2326681990

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.