ArticleNeuroscience2017
Anxious behavior induces elevated hippocampal Cb
Abstract read
In one paragraph
Article in Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 34 citations in OpenAlex.
- Selective orexin receptor cross-over treatment increases resilience and expression of neuroplastic signaling genes.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Social defeat stress responses in the stress alternative model are dependent on sex and anterior basolateral amygdala orexin 2 receptors.Biology of sex differences · 2026Article
- Aggression as a contributing factor to social defeat and stress vulnerability.Neurobiology of stress · 2025Article
- Cannabinoids as Multitarget Drugs for the Treatment of Autoimmunity in Glaucoma.ACS pharmacology & translational science · 2025Review
- Learned phenotypes emerge during social stress modifying hippocampal orexin receptor gene expression.Scientific reports · 2024Article
- Beta-Caryophyllene, a Cannabinoid Receptor Type 2 Selective Agonist, in Emotional and Cognitive Disorders.International journal of molecular sciences · 2024Review
- Anxiolytic reversal of classically conditioned / chronic stress-induced gene expression and learning in the Stress Alternatives Model.Behavioural brain research · 2023Article
- Orexin 1 Receptor Antagonism in the Basolateral Amygdala Shifts the Balance From Pro- to Antistress Signaling and Behavior.Biological psychiatry · 2022Article
- Immunomodulatory Role of CB2 Receptors in Emotional and Cognitive Disorders.Frontiers in psychiatry · 2022Review
- Does inflammation link stress to poor COVID-19 outcome?Stress and health : journal of the International Society for the Investigation of Stress · 2021Review
- Evolution of stress responses refine mechanisms of social rank.Neurobiology of stress · 2021Review
- Distribution of the Cannabinoid Receptor Type 1 in the Brain of the Genetically Audiogenic Seizure-Prone Hamster GASH/Sal.Frontiers in behavioral neuroscience · 2021Article
- CB2 Receptor in Microglia: The Guardian of Self-Control.International journal of molecular sciences · 2020Review
- Cannabinoid CBNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Article
- Orexin/hypocretin receptor modulation of anxiolytic and antidepressive responses during social stress and decision-making: Potential for therapy.Brain research · 2020Review
- Endocannabinoid System Components as Potential Biomarkers in Psychiatry.Frontiers in psychiatry · 2020Review
- Progress in brain cannabinoid CBNeuroscience and biobehavioral reviews · 2019Review
- Orexin 2 receptor stimulation enhances resilience, while orexin 2 inhibition promotes susceptibility, to social stress, anxiety and depression.Neuropharmacology · 2018Article
- Manual Hippocampal Subfield Segmentation Using High-Field MRI: Impact of Different Subfields in Hippocampal Volume Loss of Temporal Lobe Epilepsy Patients.Frontiers in neurology · 2018Article
- Cannabinoid Modulation of the Stressed Hippocampus.Frontiers in molecular neuroscience · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
James M RobertsonDepartment of Biology, University of South Dakota, Vermillion, SD 57069, USA; Neuroscience Group, Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD 57069, USA.
Justin K AchuaDepartment of Biology, University of South Dakota, Vermillion, SD 57069, USA; Neuroscience Group, Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD 57069, USA; Veterans Affairs Research Service, Sioux Falls VA Health Care System, Sioux Falls, SD 57105, USA; Avera McKennan Hospital & University Health Center, Sioux Falls, SD 57105, USA.
Justin P SmithDepartment of Biology, University of South Dakota, Vermillion, SD 57069, USA; Neuroscience Group, Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD 57069, USA; Veterans Affairs Research Service, Sioux Falls VA Health Care System, Sioux Falls, SD 57105, USA; Institute of Possibility, 322 E. 8th Street, Suite 302, Sioux Falls, SD 57103, USA; Sanford Health, 2301 E. 60th St. N., Sioux Falls, SD 57104, USA.
Melissa A PrinceDepartment of Biology, University of South Dakota, Vermillion, SD 57069, USA; Neuroscience Group, Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD 57069, USA; Veterans Affairs Research Service, Sioux Falls VA Health Care System, Sioux Falls, SD 57105, USA.
Clarissa D StatonDepartment of Biology, University of South Dakota, Vermillion, SD 57069, USA; Neuroscience Group, Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD 57069, USA; Veterans Affairs Research Service, Sioux Falls VA Health Care System, Sioux Falls, SD 57105, USA.
Patrick J RonanNeuroscience Group, Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD 57069, USA; Veterans Affairs Research Service, Sioux Falls VA Health Care System, Sioux Falls, SD 57105, USA; Department of Psychiatry, University of South Dakota School of Medicine Vermillion, SD, USA; Laboratory for Clinical and Translational Research in Psychiatry, Department of Veterans Affairs Medical Center, Denver, CO 80220, USA.
Tangi R SummersDepartment of Biology, University of South Dakota, Vermillion, SD 57069, USA; Neuroscience Group, Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD 57069, USA; Veterans Affairs Research Service, Sioux Falls VA Health Care System, Sioux Falls, SD 57105, USA.
Cliff H SummersDepartment of Biology, University of South Dakota, Vermillion, SD 57069, USA; Neuroscience Group, Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD 57069, USA; Veterans Affairs Research Service, Sioux Falls VA Health Care System, Sioux Falls, SD 57105, USA. Electronic address: Cliff@USD.Edu.
Sioux Falls VA Health Care System · USUniversity of South Dakota · USSanford Health · USVeterans Health Administration · US
Funding
VIRAL-MEDIATED RNA INTERFERENCE IN THE ADULT RAT BRAINP20RR015567 · NCRR · UNIVERSITY OF SOUTH DAKOTA · PI EYSTER, KATHLEEN M · 2000 to 2009
$16.3MSPURA - Summer Program for Undergraduate Research in AddictionR25DA033674 · NIDA · UNIVERSITY OF SOUTH DAKOTA · PI Bridget Diamond-Welch, Yohaan M. Fernandes · 2013 to 2026
$1.0MAmygdalar Orexin Modulation of Affective DisordersR15MH104485 · NIMH · UNIVERSITY OF SOUTH DAKOTA · PI SUMMERS, CLIFF H · 2015 to 2015
$426kNCRR NIH HHS P20 RR015567NIDA NIH HHS R25 DA033674NIMH NIH HHS R15 MH104485
Abstract
Anxiety is differentially expressed across a continuum of stressful/fearful intensity, influenced by endocannabinoid systems and receptors. The hippocampus plays important roles in the regulation of affective behavior, emotion, and anxiety, as well as memory. Location of Cb
Indexed as
Acoustic StimulationAnimalsConditioning, PsychologicalDisease Models, AnimalEscape ReactionFearGene Expression RegulationHippocampusInterpersonal RelationsMaleMaze LearningMiceMice, Inbred C57BLPhysical Conditioning, AnimalReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2Receptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2Receptors, TransferrinRNA, MessengerTfrc protein, mouseanxietyCb(2)endocannabinoidexercisehippocampusinduction
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.