Evidence map›Paper›PMID 28392066›Full record

ArticleEnvironment international2017

Maternal cell phone use during pregnancy and child behavioral problems in five birth cohorts.

Laura Birks, Mònica Guxens, Eleni Papadopoulou, Jan Alexander, Ferran Ballester, Marisa Estarlich, Mara Gallastegi, Mina Ha, Margaretha Haugen, Anke Huss and 9 more

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In one paragraph

Article in Environment international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
25.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

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  7. Review
  8. Can Prenatal and Postnatal Cell Phone Exposure Increase Adverse Maternal, Infant and Child Outcomes?Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 10 institutions in 7 countries.

Laura BirksISGlobal Center for Research in Environmental Epidemiology, Doctor Aiguader 88, 08003 Barcelona, Spain; Pompeu Fabra University, Carrer Ramon Trias Fargas, 25-27, 08005 Barcelona, Spain; Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Av. Monforte de Lemos, 3-5, Madrid, Spain. Electronic address: laura.birks@isglobal.org.
Mònica GuxensISGlobal Center for Research in Environmental Epidemiology, Doctor Aiguader 88, 08003 Barcelona, Spain; Pompeu Fabra University, Carrer Ramon Trias Fargas, 25-27, 08005 Barcelona, Spain; Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Av. Monforte de Lemos, 3-5, Madrid, Spain; Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre-Sophia Children's Hospital, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands.
Eleni PapadopoulouDomain of Infection Control and Environmental Health, Norwegian Institute of Public Health, Lovisenberggata 8, 0456 Oslo, Norway.
Jan AlexanderDomain of Infection Control and Environmental Health, Norwegian Institute of Public Health, Lovisenberggata 8, 0456 Oslo, Norway.
Ferran BallesterSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Av. Monforte de Lemos, 3-5, Madrid, Spain; Epidemiology and Environmental Health Joint Research Unit, FISABIO-Universitat Jaume I-Universitat de València, Av. De Blasco Ibáñez, 13, 46010, Valencia, Spain.
Marisa EstarlichSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Av. Monforte de Lemos, 3-5, Madrid, Spain; Epidemiology and Environmental Health Joint Research Unit, FISABIO-Universitat Jaume I-Universitat de València, Av. De Blasco Ibáñez, 13, 46010, Valencia, Spain.
Mara GallastegiBIODONOSTIA Health Research Institute, Begiristain Doctorea Pasealekua, 20014 San Sebastian, Spain; University of the Basque Country (UPV/EHU), Faculty of Medicine, Barrio Sarriena, s/n, 48940 Leioa, Spain.
Mina HaDepartment of Preventive Medicine, Dankook University, College of Medicine, 152 Jukjeon-ro, Jukjeon 1, Cheonan, Republic of Korea.
Margaretha HaugenDepartment of Exposure and Risk Assessment, Norwegian Institute of Public Health, Lovisenberggata 8, 0456 Oslo, Norway.
Anke HussInstitute for Risk Assessment Sciences, Utrecht University, Domplein 29, 3512 JE Utrecht, Netherlands.
Leeka KheifetsDepartment of Epidemiology, School of Public Health, University of California, 650 Charles E Young Dr S, Los Angeles, CA 90095, USA; Danish Epidemiology Science Centre, Department of Public Health, Aarhus University, Aarhus, Denmark.
Hyungryul LimDepartment of Preventive Medicine, Dankook University, College of Medicine, 152 Jukjeon-ro, Jukjeon 1, Cheonan, Republic of Korea.
Jørn OlsenDanish Epidemiology Science Centre, Department of Public Health, Aarhus University, Nordre Ringgade 1, 8000 Aarhus, Denmark.
Loreto Santa-MarinaSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Av. Monforte de Lemos, 3-5, Madrid, Spain; BIODONOSTIA Health Research Institute, Begiristain Doctorea Pasealekua, 20014 San Sebastian, Spain; Public Health Division of Gipuzkoa, Basque Government, De Francia Ibilbidea, 12, 20012 San Sebastian, Spain.
Madhuri SudanDepartment of Epidemiology, School of Public Health, University of California, 650 Charles E Young Dr S, Los Angeles, CA 90095, USA; Danish Epidemiology Science Centre, Department of Public Health, Aarhus University, Nordre Ringgade 1, 8000 Aarhus, Denmark; Danish Epidemiology Science Centre, Department of Public Health, Aarhus University, Aarhus, Denmark.
Roel VermeulenInstitute for Risk Assessment Sciences, Utrecht University, Domplein 29, 3512 JE Utrecht, Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
Tanja VrijkotteDepartment of Public Health, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Elisabeth CardisISGlobal Center for Research in Environmental Epidemiology, Doctor Aiguader 88, 08003 Barcelona, Spain; Pompeu Fabra University, Carrer Ramon Trias Fargas, 25-27, 08005 Barcelona, Spain; Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Av. Monforte de Lemos, 3-5, Madrid, Spain.
Martine VrijheidISGlobal Center for Research in Environmental Epidemiology, Doctor Aiguader 88, 08003 Barcelona, Spain; Pompeu Fabra University, Carrer Ramon Trias Fargas, 25-27, 08005 Barcelona, Spain; Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Av. Monforte de Lemos, 3-5, Madrid, Spain.
Universitat Pompeu Fabra · ESNorwegian Institute of Public Health · NODankook University · KRInstituto de Salud Carlos III · ESUniversity of California, Los Angeles · USUtrecht University · NLAarhus University · DKAmsterdam UMC Location University of Amsterdam · NLBasque Government · ESUniversity of the Basque Country · ES

Funding

Gene-Environment Interactions in an Autism Birth CohortU01NS047537 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LIPKIN, W. IAN · 2003 to 2013
$27.0M
SUPPORT SERVICES FOR EPIDEMIOLOGYN01ES085433 · NIEHS · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI TER MAAT, JAMES L · 1998 to 2000
$2.6M
NIEHS NIH HHS N01 ES085433NINDS NIH HHS U01 NS047537
6 · The paper itself

Abstract

introductionPrevious studies have reported associations between prenatal cell phone use and child behavioral problems, but findings have been inconsistent and based on retrospective assessment of cell phone use. This study aimed to assess this association in a multi-national analysis, using data from three cohorts with prospective data on prenatal cell phone use, together with previously published data from two cohorts with retrospectively collected cell phone use data.

methodsWe used individual participant data from 83,884 mother-child pairs in the five cohorts from Denmark (1996-2002), Korea (2006-2011), the Netherlands (2003-2004), Norway (2004-2008), and Spain (2003-2008). We categorized cell phone use into none, low, medium, and high, based on frequency of calls during pregnancy reported by the mothers. Child behavioral problems (reported by mothers using the Strengths and Difficulties Questionnaire or Child Behavior Checklist) were classified in the borderline/clinical and clinical ranges using validated cut-offs in children aged 5-7years. Cohort specific risk estimates were meta-analyzed.

resultsOverall, 38.8% of mothers, mostly from the Danish cohort, reported no cell phone use during pregnancy and these mothers were less likely to have a child with overall behavioral, hyperactivity/inattention or emotional problems. Evidence for a trend of increasing risk of child behavioral problems through the maternal cell phone use categories was observed for hyperactivity/inattention problems (OR for problems in the clinical range: 1.11, 95%CI 1.01, 1.22; 1.28, 95%CI 1.12, 1.48, among children of medium and high users, respectively). This association was fairly consistent across cohorts and between cohorts with retrospectively and prospectively collected cell phone use data.

conclusionsMaternal cell phone use during pregnancy may be associated with an increased risk for behavioral problems, particularly hyperactivity/inattention problems, in the offspring. The interpretation of these results is unclear as uncontrolled confounding may influence both maternal cell phone use and child behavioral problems.

Indexed as

Problem BehaviorCell Phone UseChildChild, PreschoolDenmarkFemaleHumansMental DisordersMothersNetherlandsNorwayPregnancyPrenatal Exposure Delayed EffectsProspective StudiesRepublic of KoreaRetrospective StudiesAttention deficit disorder with hyperactivityCell phonesChild behaviorChild healthElectromagnetic radiationPregnancy

Identifiers

PMID28392066
PMCPMC5506372
OpenAlexW2604213317

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.