ReviewAutonomic neuroscience : basic & clinical2017
Cardiovascular and autonomic reactivity to psychological stress: Neurophysiological substrates and links to cardiovascular disease.
Review in Autonomic neuroscience : basic & clinical, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 68 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Beta-Blocker Influences on Inflammatory and Neural Responses to Stress
School-based Practices in Arts and Resilience for Kids (SPARK Study)
Who cites it
68 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Emotion suppression and acute physiological responses to stress in healthy populations: a quantitative review of experimental and correlational investigations.Health psychology review · 2024Pooled it
- Functional neuroanatomy of peripheral inflammatory physiology: A meta-analysis of human neuroimaging studies.Neuroscience and biobehavioral reviews · 2018Pooled it
- Physiological responses to acute psychological stress as a biomarker for depression: A systematic review and meta-analysis.Psychological bulletinPooled it
- Examining the Impact of Acute Exercise and Arousal Reappraisal on Stressor-Evoked Psychological and Cardiovascular Responses.Psychophysiology · 2026Trial
- Perceived Social Support Moderates the Response to Stress and Alcohol Cues During Early Abstinence From Alcohol.Biological psychiatry global open science · 2026Article
- Differential associations of oxidative stress parameters with neuroendocrine markers and hemodynamic reactivity in acute mental stress-induced adrenergic reactivity profiles: The SABPA study.Physiological reports · 2026Article
- Trait impulsivity and risk of cardiovascular disease over 8 years: results from the NutriNet-Santé cohort.European journal of epidemiology · 2026Article
- Resting neuroendocrine markers in relation to acute mental stress-induced adrenergic reactivity profiles in adults: The SABPA study.Physiological reports · 2026Article
- Assessment of cognitive load through photoplethysmography and bioimpedance responses during mental arithmetic tasks.Scientific reports · 2026Article
- Occupational stress, cardiovascular vulnerability and sudden cardiac death in police officers: mechanisms and the protective role of structured exercise.Frontiers in public health · 2026Review
- Can psychological interventions affect cardiac rehabilitation patients' well-being? Preliminary results from a longitudinal study.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Stressor-Evoked Brain Activity, Cardiovascular Reactivity, and Subclinical Atherosclerosis in Midlife Adults.Journal of the American Heart Association · 2025Article
- Brain and cardiovascular responses to acute stress in remitted and recurrent late-life depression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Neurons of the Central Nucleus of the Amygdala That Express Angiotensin Type 2 Receptors Couple Lowered Blood Pressure with Anxiolysis in Male Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Perceived discrimination and cardiovascular risk factors in mid-life women: results from Project Viva, a longitudinal cohort in the USA.BMJ public health · 2025Article
- Psychosocial Interventions for Mental Health Problems of In-patients in Non-psychiatry Units of Selected Tertiary Hospitals in the Philippines: A Mixed-Methods Approach.Acta medica Philippina · 2025Article
- Varying doses of evening caffeine ingestion have different effects on rowing ergometer performance, sleep quality, and wakefulness scores.Frontiers in nutrition · 2025Article
- Research progress on the role and mechanism of circadian clock geneFrontiers in immunology · 2025Review
- The Association between Maladaptive Coping Strategies and Cardiovascular Risk Factors: A 12-Year Evaluation from the Isfahan Cohort Study.International journal of preventive medicine · 2025Article
- A preliminary investigation of worry, cortical amyloid burden, and stressor-evoked brain and cardiovascular reactivity in older adults.Journal of affective disorders · 2024Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Psychologically stressful experiences evoke changes in cardiovascular physiology that may influence risk for cardiovascular disease (CVD). But what are the neural circuits and intermediate physiological pathways that link stressful experiences to cardiovascular changes that might in turn confer disease risk? This question is important because it has broader implications for our understanding of the neurophysiological pathways that link stressful and other psychological experiences to physical health. This review highlights selected findings from brain imaging studies of stressor-evoked cardiovascular reactivity and CVD risk. Converging evidence across these studies complements animal models and patient lesion studies to suggest that a network of cortical, limbic, and brainstem areas for central autonomic and physiological control are important for generating and regulating stressor-evoked cardiovascular reactivity via visceromotor and viscerosensory mechanisms. Emerging evidence further suggests that these brain areas may play a role in stress-related CVD risk, specifically by their involvement in mediating metabolically-dysregulated or extreme stressor-evoked cardiovascular reactions. Contextually, the research reviewed here offers an example of how brain imaging and health neuroscience methods can be integrated to address open and mechanistic questions about the neurophysiological pathways linking psychological stress and physical health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.