Evidence map›Paper›PMID 28391549›Full record

ArticleAdvances in therapy2017

Disease Burden of Mild Asthma: Findings from a Cross-Sectional Real-World Survey.

Bo Ding, Mark Small

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Advances in therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Corticosteroid plus βRespiratory research · 2017
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Identifying and Addressing the Hidden Risks of Mild Asthma.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025
    Article
  7. The value of treatable traits across the spectrum of adult asthma severity.Chinese medical journal pulmonary and critical care medicine · 2025
    Review
  8. Article
  9. Review
  10. Elevating the Importance of Asthma Care in the United States.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2024
    Article
  11. Risk Factors for Acute Asthma Exacerbations in Adults With Mild Asthma.The journal of allergy and clinical immunology. In practice · 2024
    Article
  12. Article
  13. Maternal asthma in relation to infant size and body composition.The journal of allergy and clinical immunology. Global · 2023
    Article
  14. Short-acting βMalaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2023
    Article
  15. Review
  16. Short-acting βNPJ primary care respiratory medicine · 2022
    Article
  17. Observational
  18. Article
  19. Over-prescription of short-acting βAfrican journal of thoracic and critical care medicine · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Bo DingAstraZeneca Gothenburg, Mölndal, Sweden. Bo.Ding@astrazeneca.com.
Mark SmallAdelphi Real World, Bollington, UK.
Adelphi Group (United Kingdom) · GBAstraZeneca (Sweden) · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMost asthma patients have mild disease, although the burden of mild asthma is not well understood nor studied. Some evidence suggests that many patients with mild asthma experience suboptimal symptom control and exacerbations. This study characterizes the burden of illness and treatment patterns among patients with a confirmed diagnosis of mild asthma, defined as GINA Step 1 or Step 2, and residing in China, France, Germany, Italy, Japan, Spain, the United Kingdom, or the United States.

methodsThe Respiratory Disease-Specific Programme prospective cross-sectional survey was conducted with primary care and specialty physicians in each of the eight countries. Physician and patient surveys assessed demographic and clinical characteristics, frequency and timing of asthma symptoms, exacerbations, and rescue inhaler usage, the most recent FEV

resultsThe sample included 1115 GINA Step 1 and 2 patients, with 53% classified as Step 2. Overall asthma control was suboptimal, with reports of nocturnal symptoms (40.6%), symptom worsening (10.5%), and rescue inhaler usage in the last 4 weeks (33.6%). 25% of patients were uncontrolled. The overall mean number of exacerbations in the last 12 months was 0.4, with a higher frequency of exacerbations in Step 2 patients who also experienced more exacerbations requiring treatment intensification, an emergency department visit, or hospitalization.

conclusionMild asthma imposes a substantial burden on patients, establishing the need for comprehensive management plans and ongoing support for treatment adherence.

fundingAstraZeneca.

Indexed as

Cost of IllnessAdrenal Cortex HormonesAdultAnti-Asthmatic AgentsAsthmaChinaCross-Sectional StudiesFemaleFranceGermanyHumansItalyJapanMaleMiddle AgedProspective StudiesAdrenal Cortex HormonesAnti-Asthmatic AgentsAdherenceAsthma controlBurden of illnessExacerbationsGINA treatment stepMild asthmaRespiratorySymptoms

Identifiers

PMID28391549
PMCPMC5427102
OpenAlexW2604610932

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.