Article3 Biotech2017
Concurrent production of cellulase and xylanase from Trichoderma reesei NCIM 1186: enhancement of production by desirability-based multi-objective method.
Article in 3 Biotech, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed.
- Integrated bioprocess optimization of cellulase and xylanase production by Penicillium argillaceum using lignocellulosic agro-industrial residues.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Application of Central Composite Design and Superimposition Approach for Optimization of Drying Parameters of Pretreated Cassava Flour.Foods (Basel, Switzerland) · 2023Article
- Current perspective on production and applications of microbial cellulases: a review.Bioresources and bioprocessing · 2021Review
- Assessment and evaluation of cellulase production using ragi (Eleusine coracana) husk as a substrate from thermo-acidophilic Aspergillus fumigatus JCM 10253.Bioprocess and biosystems engineering · 2021Article
- Cellulolytic thermophilic microorganisms in white biotechnology: a review.Folia microbiologica · 2020Review
- Fungi.guru: Comparative genomic and transcriptomic resource for the fungi kingdom.Computational and structural biotechnology journal · 2020Article
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5 authors.
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Abstract
Application of multiple response optimizations using desirability function in the production of microbial metabolites improves economy and efficiency. Concurrent production of cellulase and xylanase in Trichoderma reesei NCIM 1186 using an agricultural weed, Prosopis juliflora pods, was studied. The main aim of the study was to optimize significant medium nutrient parameters for maximization of cellulase and xylanase by multi-objective optimization strategy using biomass. Process parameters such as the nutrient concentrations (pods, sucrose, and yeast extract) and pH were investigated to improve cellulase and xylanase activities by one factor at a time approach, single response optimization and multi-objective optimization. At the corresponding optimized process parameters in single response optimization, the maximum cellulase activity observed was 3055.65 U/L where xylanase highest activity was 422.16 U/L. Similarly, the maximum xylanase activity, 444.94 U/L, was observed with the highest cellulase activity of 2804.40 U/L. The multi-objective optimization finds a tradeoff between the two objectives and optimal activity values in between the single-objective optima were achieved, 3033.74 and 439.13 U/L for cellulase and xylanase, respectively.
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