Evidence map›Paper›PMID 28391449›Full record

Observational studyInternational journal of colorectal disease2017

Percutaneous tibial nerve stimulation (pTNS): success rate and the role of rectal capacity.

Lukas Marti, Christian Galata, Ulrich Beutner, Franc Hetzer, Nicoletta Pipitone, Katja Wolff, Jan Borovicka, Walter Brunner, Michael Christian Sulz, Christine Maurus

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in International journal of colorectal disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Electrical neuromodulation therapy for inflammatory bowel disease.World journal of gastrointestinal pathophysiology · 2022
    Review
  5. [Anal incontinence].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2022
    Article
  6. Article
  7. Article
  8. Observational
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lukas MartiDepartment of General, Visceral, Endocrine and Transplantation Surgery, Kantonsspital St. Gallen, 9007, St. Gallen, Switzerland. lukas.marti@kssg.ch.ORCID http://orcid.org/0000-0001-5413-132X
Christian GalataDepartment of Surgery, University Medical Center Mannheim, University of Heidelberg, 68167, Mannheim, Germany.
Ulrich BeutnerDepartment of General, Visceral, Endocrine and Transplantation Surgery, Kantonsspital St. Gallen, 9007, St. Gallen, Switzerland.
Franc HetzerDepartment of Surgery, Spital Linth, 8730, Uznach, Switzerland.
Nicoletta PipitoneDepartment of General, Visceral, Endocrine and Transplantation Surgery, Kantonsspital St. Gallen, 9007, St. Gallen, Switzerland.
Katja WolffDepartment of General, Visceral, Endocrine and Transplantation Surgery, Kantonsspital St. Gallen, 9007, St. Gallen, Switzerland.
Jan BorovickaDivision of Gastroenterology, Kantonsspital St. Gallen, 9007, St. Gallen, Switzerland.
Walter BrunnerDepartment of General, Visceral, Endocrine and Transplantation Surgery, Kantonsspital St. Gallen, 9007, St. Gallen, Switzerland.
Michael Christian SulzDivision of Gastroenterology, Kantonsspital St. Gallen, 9007, St. Gallen, Switzerland.
Christine MaurusDepartment of General, Visceral, Endocrine and Transplantation Surgery, Kantonsspital St. Gallen, 9007, St. Gallen, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePercutaneous tibial nerve stimulation (pTNS) was originally developed to treat urinary incontinence. Recently, some case series have also documented its success in the treatment of fecal incontinence. Nevertheless, the mechanism underlying this effect remains unknown but may be related to changes in rectal capacity. The aim of this study was to investigate the success of pTNS for the treatment of fecal urge incontinence and assess the influence of rectal capacity on treatment efficacy.

methodsAll patients undergoing pTNS for fecal incontinence between July 2009 and March 2014 were enrolled in a prospective, observational study consisting of a therapeutic regimen that lasted 9 months. Therapy success was defined as a reduction in the CCI (Cleveland Clinic incontinence) score of ≥50% and patient-reported success. Furthermore, quality of life (Rockwood's scale) and changes in anorectal physiology were recorded.

resultsFifty-seven patients with fecal urge incontinence were eligible, nine of whom were excluded. The success rate was 72.5%. Incontinence events and urge symptoms were significantly reduced after 3 months and at the end of therapy. The median CCI score decreased from 12 to 4 (P < 0.0001), and the quality of life was significantly improved. However, rectal capacity was not significantly related to treatment success before or after therapy. No adverse events were observed.

conclusionsThese results demonstrate that pTNS can improve the symptoms and quality of life of patients with fecal urge incontinence. However, the study fails to demonstrate a correlation between treatment success and changes in rectal capacity.

Indexed as

Transcutaneous Electric Nerve StimulationAnal CanalDefecationFecal IncontinenceFemaleHumansMaleMiddle AgedQuality of LifeRectumTibial NerveTreatment OutcomeFecal incontinenceNeuromodulationPercutaneous tibial nerve stimulationpTNSRectal capacity

Identifiers

PMID28391449

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.