Evidence map›Paper›PMID 28391382›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2017

Insufficient stability of pedicle screws in osteoporotic vertebrae: biomechanical correlation of bone mineral density and pedicle screw fixation strength.

Lukas Weiser, Gerd Huber, Kay Sellenschloh, Lennart Viezens, Klaus Püschel, Michael M Morlock, Wolfgang Lehmann

Abstract read
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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 1 pooled it
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 1 synthesis or guideline pooled it, 190 citations in OpenAlex.

  1. Pooled it
  2. TLS-VBQ: a novel MRI-based bone quality score for opportunistic osteoporosis screening in spinal surgery candidates.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  5. A comprehensive review of biomechanical factors influencing pedicle screw fixation strength and the critical role of artificial intelligence.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  11. Asymmetric distribution of vertebral bone microstructure in coronal adult spinal deformity: a cross-sectional study based on quantitative CT.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  20. Opportunistic osteoporosis screening in intraoperative CT can accurately identify patients with low volumetric bone mineral density and osteoporosis during spine surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
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33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lukas WeiserDepartment of Trauma-, Orthopaedic- and Plastic Surgery, University Medical Center Göttingen, Robert-Koch-Str. 40, 37099, Göttingen, Germany. Lukas.Weiser@med.uni-goettingen.de.ORCID 0000-0001-9812-4658
Gerd HuberInstitute of Biomechanics, TUHH Hamburg University of Technology, Hamburg, Germany.
Kay SellenschlohInstitute of Biomechanics, TUHH Hamburg University of Technology, Hamburg, Germany.
Lennart ViezensDepartment of Trauma-, Orthopaedic- and Plastic Surgery, University Medical Center Göttingen, Robert-Koch-Str. 40, 37099, Göttingen, Germany.
Klaus PüschelInstitute of Forensic Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Michael M MorlockInstitute of Biomechanics, TUHH Hamburg University of Technology, Hamburg, Germany.
Wolfgang LehmannDepartment of Trauma-, Orthopaedic- and Plastic Surgery, University Medical Center Göttingen, Robert-Koch-Str. 40, 37099, Göttingen, Germany.
Universität Hamburg · DEUniversitätsmedizin Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLoosening of pedicle screws is one major complication of posterior spinal stabilisation, especially in the patients with osteoporosis. Augmentation of pedicle screws with cement or lengthening of the instrumentation is widely used to improve implant stability in these patients. However, it is still unclear from which value of bone mineral density (BMD) the stability of pedicle screws is insufficient and an additional stabilisation should be performed. The aim of this study was to investigate the correlation of bone mineral density and pedicle screw fatigue strength as well as to define a threshold value for BMD below which an additional stabilisation is recommended.

methodsTwenty-one human T12 vertebral bodies were collected from donors between 19 and 96 years of age and the BMD was measured using quantitative computed tomography. Each vertebral body was instrumented with one pedicle screw and mounted in a servo-hydraulic testing machine. Fatigue testing was performed by implementing a cranio-caudal sinusoidal, cyclic (0.5 Hz) load with stepwise increasing peak force.

resultsA significant correlation between BMD and cycles to failure (r = 0.862, r

conclusionsThere is a close correlation between BMD and pedicle screw stability. If the BMD of the thoracolumbar spine is less than 80 mg/cm

Indexed as

Bone DensityOsteoporosisPedicle ScrewsSpinal FusionThoracic VertebraeAdolescentAdultAgedAged, 80 and overBiomechanical PhenomenaEquipment Failure AnalysisHumansMiddle AgedTomography, X-Ray ComputedYoung AdultBMDBone mineral densityOsteoporosisPedicle screwSpine

Identifiers

PMID28391382
OpenAlexW2604546486

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.