ReviewImmunologic research2017
Resolution of inflammation pathways in preeclampsia-a narrative review.
Review in Immunologic research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Parameters of the thrombin generation test in pregnant women with preeclampsia: a systematic review.BMC pregnancy and childbirth · 2026Pooled it
- A meta-analysis on first-trimester blood count parameters-is the neutrophil-to-lymphocyte ratio a potentially novel method for first-trimester preeclampsia screening?Frontiers in medicine · 2024Pooled it
- Complete blood count as a biomarker for preeclampsia with severe features diagnosis: a machine learning approach.BMC pregnancy and childbirth · 2024Article
- The causal role of circulating immunity-inflammation in preeclampsia: A Mendelian randomization.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Prenatal phthalate exposure and adverse birth outcomes in the USA: a prospective analysis of births and estimates of attributable burden and costs.The Lancet. Planetary health · 2024Article
- Prenatal Phenol and Paraben Exposures and Adverse Birth Outcomes: A Prospective Analysis of U.S. Births.Environment international · 2024Article
- MIF Increases sFLT1 Expression in Early Uncomplicated Pregnancy and Preeclampsia.International journal of molecular sciences · 2023Article
- Endometriosis and Impaired Placentation: A Prospective Cohort Study Comparing Uterine Arteries Doppler Pulsatility Index in Pregnancies of Patients with and without Moderate-Severe Disease.Diagnostics (Basel, Switzerland) · 2022Article
- Inflammation in Preeclampsia: Genetic Biomarkers, Mechanisms, and Therapeutic Strategies.Frontiers in immunology · 2022Article
- Study of Treatment and Reproductive Outcomes Among Reproductive-Age Women With HIV Infection in the Southern United States: Protocol for a Longitudinal Cohort Study.JMIR research protocols · 2021Article
- Nonlinear analysis of heart rhythm in preeclampsia: a route for translational clinical applications in neuroinflammation.Clinical hypertension · 2021Review
- Comparative Characteristics of the Expression of Fucosylated Glycans and Morphometric Parameters of Terminal Placental Villi Depending on the Severity of Preeclampsia.Bulletin of experimental biology and medicine · 2021Article
- Association between the levels of CGI-58 and lipoprotein lipase in the placenta of patients with preeclampsia.Experimental and therapeutic medicine · 2021Article
- Combined Effects of Methyldopa and Flavonoids on the Expression of Selected Factors Related to Inflammatory Processes and Vascular Diseases in Human Placenta Cells-An In Vitro Study.Molecules (Basel, Switzerland) · 2021Article
- The Role of Oxidative Stress and Antioxidant Balance in Pregnancy.Mediators of inflammation · 2021Review
- Risk of pre-eclampsia in patients with a maternal genetic predisposition to common medical conditions: a case-control study.BJOG : an international journal of obstetrics and gynaecology · 2021Article
- Low-Dose Aspirin Prevents Kidney Damage in LPS-Induced Preeclampsia by Inhibiting the WNT5A and NF-κB Signaling Pathways.Frontiers in endocrinology · 2021Article
- Maternal Immune System and State of Inflammation Dictate the Fate and Severity of Disease in Preeclampsia.Journal of immunology research · 2021Article
- Magnesium sulfate prophylaxis attenuates the postpartum effects of preeclampsia by promoting M2 macrophage polarization.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Can Endothelial Glycocalyx Be a Major Morphological Substrate in Pre-Eclampsia?International journal of molecular sciences · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preeclampsia (PE) is one of the leading causes of maternal morbidity and mortality worldwide. This disease is believed to occur in two stages with placental dysfunction in early pregnancy leading to maternal clinical findings after 20 weeks of gestation, as consequence of systemic inflammation, oxidative stress, and endothelial dysfunction. Much evidence suggests that PE women display an overshooting inflammatory response throughout pregnancy due to an unbalanced regulation of innate and adaptive immune responses. Recently, it has been suggested that dysregulation of endogenous protective pathways might be associated with PE etiopathogenesis. Resolution of inflammation is an active process coordinated by mediators from diverse nature that regulate key cellular events to restore tissue homeostasis. Inadequate or insufficient resolution of inflammation is believed to play an important role in the development of chronic inflammatory diseases, like PE. In this narrative review, we discuss possible pro-resolution pathways that might be compromised in PE women, which could be targets to novel therapeutic strategies in this disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.