Evidence map›Paper›PMID 28391131›Full record

ReviewCurrent opinion in neurobiology2017

Attacking sleep from a new angle: contributions from zebrafish.

Grigorios Oikonomou, David A Prober

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Zebrafish sleep displays distinct sub-states.bioRxiv : the preprint server for biology · 2025
    Article
  14. Article
  15. Article
  16. The Role and Mechanisms of the Hypocretin System in Zebrafish (International journal of molecular sciences · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Grigorios OikonomouDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
David A ProberDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: dprober@caltech.edu.

Funding

Neuropeptidergic Regulation of Zebrafish SleepR01NS070911 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PROBER, DAVID AARON · 2011 to 2020
$3.5M
Role of Prokineticin 2 in Regulating Sleep in ZebrafishR01NS095824 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PROBER, DAVID AARON · 2017 to 2021
$1.8M
Regulation of Zebrafish Sleep by Neuromedin UR01NS101158 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PROBER, DAVID AARON · 2017 to 2020
$1.4M
Circadian Regulation of Zebrafish Sleep by MelatoninR01NS101665 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PROBER, DAVID AARON · 2017 to 2020
$1.4M
Regulation of Zebrafish Sleep by Neuromedin UR56NS094390 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PROBER, DAVID AARON · 2016 to 2016
$411k
Hypocretin and Locus Ceruleus Interactions in Zebrafish Development and BehaviorF32NS082010 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI OIKONOMOU, GRIGORIOS · 2012 to 2015
$159k
NINDS NIH HHS F32 NS082010NINDS NIH HHS R01 NS070911NINDS NIH HHS R01 NS095824NINDS NIH HHS R01 NS101158NINDS NIH HHS R01 NS101665NINDS NIH HHS R56 NS094390
6 · The paper itself

Abstract

Sleep consumes a third of our lifespan, but we are far from understanding how it is initiated, maintained and terminated, or what purposes it serves. To address these questions, alternative model systems have recently been recruited. The diurnal zebrafish holds the promise of bridging the gap between simple invertebrate systems, which show little neuroanatomical conservation with mammals, and well-established, but complex and nocturnal, murine systems. Zebrafish larvae can be monitored in a high-throughput fashion, pharmacologically tested by adding compounds into the water, genetically screened using transient transgenesis, and optogenetically manipulated in a non-invasive manner. Here we discuss work that has established the zebrafish as a powerful system for the study of sleep, as well as novel insights gained by exploiting its particular advantages.

Indexed as

AnimalsModels, AnimalSleepZebrafish

Identifiers

PMID28391131
PMCPMC5659277

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.