Evidence map›Paper›PMID 28390680›Full record

ArticleThe American journal of cardiology2017

Effect of Chronic Obstructive Pulmonary Disease on In-Hospital Mortality and Clinical Outcomes After ST-Segment Elevation Myocardial Infarction.

Manyoo Agarwal, Sahil Agrawal, Lohit Garg, Aakash Garg, Nirmanmoh Bhatia, Dipen Kadaria, Guy Reed

Abstract readMulticenter Study
In one paragraph

Article in The American journal of cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. The CHADiagnostics (Basel, Switzerland) · 2022
    Article
  7. Predictors of in-hospital mortality in diabetic patients with non-ST-elevation myocardial infarction.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. COPD and acute myocardial infarction.European respiratory review : an official journal of the European Respiratory Society · 2020
    Review
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  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Manyoo AgarwalDepartment of Internal Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.
Sahil AgrawalDivision of Cardiovascular Medicine, Department of Internal Medicine, St Luke's University Health Network, Bethlehem, Pennsylvania.
Lohit GargDivision of Cardiovascular Medicine, Department of Internal Medicine, Lehigh Valley Health Network, Allentown, Pennsylvania.
Aakash GargDepartment of Internal Medicine, Saint Peter's Healthcare System, New Brunswick, New Jersey.
Nirmanmoh BhatiaDivision of Cardiovascular Medicine, Department of Internal Medicine, Vanderbilt Medical Center, Nashville, Tennessee.
Dipen KadariaDivision of Pulmonary Medicine and Critical Care, Department of Internal Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.
Guy ReedDepartment of Internal Medicine, University of Tennessee Health Science Center, Memphis, Tennessee; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Tennessee Health Science Center, Memphis, Tennessee. Electronic address: glreed@uthsc.edu.
University of Tennessee Health Science Center · USLehigh Valley Hospital-Pocono · USSaint Peter's University Hospital · USSt. Luke's University Health Network · USVanderbilt University Medical Center · US

Funding

Alpha-2-antiplasmin and Ischemic StrokeR01NS089707 · NINDS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI REED, GUY L · 2015 to 2019
$1.9M
NINDS NIH HHS R01 NS089707
6 · The paper itself

Abstract

There is controversy regarding in-hospital mortality, revascularization, and other adverse outcomes in patients with ST-segment elevation (STEMI) and chronic obstructive pulmonary disease (COPD). We queried the 2003 to 2011 Nationwide Inpatient Sample databases to identify patients aged ≥18 years with a primary diagnosis of STEMI. Univariate and multivariate analyses were performed to evaluate the association of COPD with in-hospital clinical outcomes. Patients with COPD comprised 13.2% of 2,120,005 patients with STEMI. COPD was associated with older age, Medicare insurance, greater co-morbidities, and lower socioeconomic status. Compared with non-COPD patients, patients with COPD had higher inpatient mortality even after adjustment for multiple potential other factors (12.5% vs 8.6%, adjusted odds ratio [AOR] 1.13, 95% CI 1.11 to 1.15, p <0.001). Patients with COPD were more likely to develop new-onset heart failure (AOR 2.01, 95% CI 1.99 to 2.03), cardiogenic shock (AOR 1.24, 95% CI 1.22 to 1.26), and acute respiratory failure (AOR 2.46, 95% CI 2.43 to 2.50) during their hospital stay. Patients with COPD were less likely to undergo diagnostic angiographies and any revascularization procedures. The mean length of stay (6.0 vs 4.6 days; p <0.001) was greater in patients with COPD, as were hospital average hospital charges ($63,956 vs $58,536; p <0.001). In conclusion, among patients with STEMI, COPD is associated with a greater risk of in-hospital mortality, new-onset heart failure, acute respiratory failure, and cardiogenic shock.

Indexed as

Population SurveillanceAgedFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedMorbidityPulmonary Disease, Chronic ObstructiveRetrospective StudiesST Elevation Myocardial InfarctionSurvival RateUnited States

Identifiers

PMID28390680
PMCPMC5599153
OpenAlexW2592953308

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.