ArticlePediatric dentistry2017
Association Between Early Childhood Caries and Colonization with
Article in Pediatric dentistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Oral Health, Anxiety, Depression, and Stress in Pregnancy: A Rapid Review of Associations and Implications for Perinatal Care.International journal of environmental research and public health · 2024Pooled it
- Prenatal Oral Health Care and Early Childhood Caries Prevention: A Systematic Review and Meta-Analysis.Caries research · 2019Pooled it
- Addition of Povidone-Iodine to Fluoride Varnish for Dental Caries: A Randomized Clinical Trial.JDR clinical and translational research · 2021Trial
- Children's oral health: Are dentists and physicians prepared enough? A cross-sectional interdisciplinary survey carried out in North Italy.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Oral Health Promotion in Pediatric Age Groups: Habits and Behaviors of Italian and Spanish Parents and Children.Journal of clinical medicine · 2025Article
- Oral Pathogens' Substantial Burden on Cancer, Cardiovascular Diseases, Alzheimer's, Diabetes, and Other Systemic Diseases: A Public Health Crisis-A Comprehensive Review.Pathogens (Basel, Switzerland) · 2024Review
- Effects of Sucrose and Farnesol on Biofilm Formation byMicroorganisms · 2024Article
- Intraspecies interactions ofmSphere · 2024Article
- Intraspecies interactions ofbioRxiv : the preprint server for biology · 2023Article
- The contribution of maternal factors to the oral microbiota of the child: Influence from early life and clinical relevance.The Japanese dental science review · 2023Review
- What Do Mothers (or Caregivers) Know about Their Children's Oral Hygiene? An Update of the Current Evidence.Children (Basel, Switzerland) · 2022Review
- Comparison of oral microbiome profiles in 18-month-old infants and their parents.Scientific reports · 2021Article
- Caries-Associated Biosynthetic Gene Clusters inJournal of dental research · 2020Article
- Mother's Perceived Social Support and Children's Dental Caries in Northern Appalachia.Pediatric dentistry · 2019Article
- Streptococcus mutans serotypes and collagen-binding proteins Cnm/Cbm in children with caries analysed by PCR.Molecular oral microbiology · 2019Article
- A Preexperimental Study to Assess the Impact of an Interdisciplinary Educational Intervention on Nurses' Knowledge of Perinatal and Infant Oral Health Care.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThe purpose of this study was to evaluate Streptococcus mutans genotypes (GT) between mother and child (M-C) in a high caries risk cohort to explore the association with early childhood caries (ECC).
methodsSixty-nine infants (each approximately one year old) had periodic oral examinations (dmfs) and microbial samples collected from dental plaque, saliva, and other oral surfaces. Their mothers had an examination and plaque collected. S mutans isolates were genotyped using repetitive extragenic palindromic-PCR (rep-PCR). Statistical analyses were conducted for associations of S mutans in M-C dyads with caries outcomes.
resultsTwenty-seven S mutans genotypes (GT) from 3,414 isolates were identified. M-C were categorized as GT match (<small>n</small> equals 40) or no-match (n equals 29). When modeling the severity of ECC at 36 months (approximately four years old), the estimated dmfs in the match group was 2.61 times that of the no-match group (P=.014).
conclusionsColonization of children with Streptococcus mutans genotypes that matched with mothers was shown to be highly associated with early childhood caries. Although the data suggest vertical transmission of S mutans in 40 of 69 children that shared GT with their mother, it is possible that other individuals transmitted the S mutans. Nonetheless, these findings support the importance of the mother's oral microbial status as a contributing influence to their children's oral health.
Indexed as
Identifiers
28390463PMC5385848W2990324681What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.