ArticleInternational psychogeriatrics2017
Anxiety symptoms and risk of cognitive decline in older community-dwelling men.
Article in International psychogeriatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evaluating the effects of physical activity and antidepressive agents on depressive symptoms in older adults: a meta-analysis of existing evidence.BMC geriatrics · 2025Pooled it
- Big smile, small self: Awe walks promote prosocial positive emotions in older adults.Emotion (Washington, D.C.) · 2022Trial
- Association between anxious-depression and cognitive function in community-dwelling older adults: a latent class analysis.Frontiers in public health · 2026Article
- Surgical apgar score and delayed neurocognitive recovery in elderly patients: a prospective cohort study.BMC surgery · 2025Article
- Latent Cognitive Profiles Predict 1-Year Mental Health, Insomnia, Falls, Daily Functioning, and Pain in US Older Adults: A National Longitudinal Study.Journal of the American Medical Directors Association · 2025Article
- Article
- Creative Commons 4.0 Exploring the complex interplay between anxiety, aging, and behavior in CB6F1 and C57BL/6 mice: implications for cognitive function.Aging pathobiology and therapeutics · 2024Article
- Community-based social healthcare practices in China for healthy aging: a social prescription perspective analysis.Frontiers in public health · 2023Article
- Cognitive Stimulation as Alternative Treatment to Improve Psychological Disorders in Patients with Mild Cognitive Impairment.Journal of clinical medicine · 2022Article
- tDCS over the left prefrontal Cortex improves mental flexibility and inhibition in geriatric inpatients with symptoms of depression or anxiety: A pilot randomized controlled trial.Frontiers in rehabilitation sciences · 2022Article
- A Randomized Controlled Trial Study of a Multimodal Intervention vs. Cognitive Training to Foster Cognitive and Affective Health in Older Adults.Frontiers in psychology · 2022Article
- Incidence of Anxiety in Latest Life and Risk Factors. Results of the AgeCoDe/AgeQualiDe Study.International journal of environmental research and public health · 2021Article
- The evolution trend of availability of China's community-based care services and its impact on the cognitive function of elderly people: 2008-2018.International journal for equity in health · 2021Article
- Neuropsychiatric symptoms and the outcome of cognitive trajectories in older adults free of dementia: The Mayo Clinic Study of Aging.International journal of geriatric psychiatry · 2021Article
- Self-Esteem, Anxiety, and Depression in Older People in Nursing Homes.Healthcare (Basel, Switzerland) · 2021Article
- Within-person increase in pathological worry predicts future depletion of unique executive functioning domains.Psychological medicine · 2021Article
- The application of an information support robot to reduce agitation in an older adult with Alzheimer's disease living alone in a community dwelling: a case study.Hong Kong journal of occupational therapy : HKJOT · 2021Article
- Defining Atypical Anxiety in Parkinson's Disease.Movement disorders clinical practice · 2021Article
- Association of Anxiety Awareness with Risk Factors of Cognitive Decline in MCI.Brain sciences · 2021Article
- Anxiety and executive functions in mid-to-late life: the moderating role of sleep.Aging & mental health · 2020Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundPrevious research regarding anxiety as a predictor of future cognitive decline in older adults is limited and inconsistent. We examined the independent relationship between anxiety symptoms and subsequent cognitive decline.
methodsWe included 2,818 community-dwelling older men (mean age = 76.1, SD ±5.3 years) who were followed on an average for 3.4 years. We assessed anxiety symptoms at baseline using the Goldberg Anxiety Scale (GAS; range = 0-9). We assessed cognitive function at baseline and at two subsequent visits using the Modified Mini-Mental State Examination (3MS; global cognition) and the Trails B test (executive function).
resultsAt baseline, there were 690 (24%) men with mild anxiety symptoms (GAS 1-4) and 226 (8%) men with moderate/severe symptoms (GAS 5-9). Men with anxiety symptoms were more likely to have depressed mood, poor sleep, more chronic medical conditions, and more impairment in activities of daily living compared to those with no anxiety symptoms. Compared to those with no anxiety symptoms at baseline, men with any anxiety symptoms were more likely to have substantial worsening in Trails B completion time (OR = 1.56, 95% CI 1.19, 2.05). The association was attenuated after adjusting for potential confounders, including depression and poor sleep, but remained significant (OR = 1.40, 95% CI 1.04, 1.88).
conclusionIn cognitively healthy older men, mild anxiety symptoms may potentially predict future decline in executive functioning. Anxiety is likely a manifestation of an underlying neurodegenerative process rather than a cause.
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