ArticleJournal of medical virology2017
Lithium chloride inhibits early stages of foot-and-mouth disease virus (FMDV) replication in vitro.
Article in Journal of medical virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Viral Induced Oxidative and Inflammatory Response in Alzheimer's Disease Pathogenesis with Identification of Potential Drug Candidates: A Systematic Review using Systems Biology Approach.Current neuropharmacology · 2019Pooled it
- Phospholipase PLA2G16 Accelerates the Host Interferon Signaling Pathway Response to FMDV.Viruses · 2025Article
- Reimagining safe lithium applications in the living environment and its impacts on human, animal, and plant system.Environmental science and ecotechnology · 2023Review
- Lithium salts as a treatment for COVID-19: Pre-clinical outcomes.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022Article
- An overview of solutions for airborne viral transmission reduction related to HVAC systems including liquid desiccant air-scrubbing.Energy (Oxford, England) · 2022Article
- Potential mechanisms underlying lithium treatment for Alzheimer's disease and COVID-19.European review for medical and pharmacological sciences · 2022Review
- Impact of SARS-CoV-2 on Host Factors Involved in Mental Disorders.Frontiers in microbiology · 2022Review
- Lithium chloride inhibits infectious bronchitis virus-induced apoptosis and inflammation.Microbial pathogenesis · 2022Article
- Lithium and Therapeutic Targeting of GSK-3.Cells · 2021Review
- Article
- Lithium's antiviral effects: a potential drug for CoViD-19 disease?International journal of bipolar disorders · 2020Review
- Characterization of a recombinant pseudorabies virus expressing porcine parvovirus VP2 protein and porcine IL-6.Virology journal · 2020Article
- Lithium and coronaviral infections. A scoping review.F1000Research · 2020Article
- Inhibitory effects of homoharringtonine on foot and mouth disease virus in vitro.Journal of medical virology · 2019Article
- Article
- Transcript Profiling Identifies Early Response Genes against FMDV Infection in PK-15 Cells.Viruses · 2018Article
- Lithium chloride inhibits early stages of foot-and-mouth disease virus (FMDV) replication in vitro.Journal of medical virology · 2017Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Foot-and-mouth disease virus (FMDV) causes an economically important and highly contagious disease of cloven-hoofed animals such as cattle, swine, and sheep. FMD vaccine is the traditional way to protect against the disease, which can greatly reduce its occurrence. However, the use of FMD vaccines to protect early infection is limited. Therefore, the alternative strategy of applying antiviral agents is required to control the spread of FMDV in outbreak situations. As previously reported, LiCl has obviously inhibition effects on a variety of viruses such as transmissible gastroenteritis virus (TGEV), infectious bronchitis coronavirus (IBV), and pseudorabies herpesvirus and EV-A71 virus. In this study, our findings were the first to demonstrate that LiCl inhibition of the FMDV replication. In this study, BHK-21 cell was dose-dependent with LiCl at various stages of FMDV. Virus titration assay was calculated by the 50% tissue culture infected dose (TCID
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.