ArticleIntensive care medicine experimental2017
Extracorporeal CO
Article in Intensive care medicine experimental, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference.Kidney international · 2020 · on this mapGuideline
- COBMC nephrology · 2019Trial
- Additional Carbon Dioxide Removal by Oxygenated Dialysis Fluid: Insights for the Development of a Novel Lung and Kidney Assist Device.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2026Article
- Metabolic and nutritional aspects in continuous renal replacement therapy.Journal of intensive medicine · 2023Review
- Novel Size-Variable Dedicated Rodent Oxygenator for ECLS Animal Models-Introduction of the "RatOx" Oxygenator and Preliminary In Vitro Results.Micromachines · 2023Article
- Challenges in ARDS Definition, Management, and Identification of Effective Personalized Therapies.Journal of clinical medicine · 2023Review
- Extracorporeal carbon dioxide removal with the Advanced Organ Support system in critically ill COVID-19 patients.Artificial organs · 2021Observational
- Ten golden rules for individualized mechanical ventilation in acute respiratory distress syndrome.Journal of intensive medicine · 2021Review
- Comparison of Circular and Parallel-Plated Membrane Lungs for Extracorporeal Carbon Dioxide Elimination.Membranes · 2021Article
- Physiological Basis of Extracorporeal Membrane Oxygenation and Extracorporeal Carbon Dioxide Removal in Respiratory Failure.Membranes · 2021Review
- Suitable COBioengineering (Basel, Switzerland) · 2021Article
- Dual Carbon Dioxide Capture to Achieve Highly Efficient Ultra-Low Blood Flow Extracorporeal Carbon Dioxide Removal.Annals of biomedical engineering · 2020Article
- Lung-kidney interactions in critically ill patients: consensus report of the Acute Disease Quality Initiative (ADQI) 21 Workgroup.Intensive care medicine · 2020Article
- [Current techniques for extracorporeal decarboxylation].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2019Review
- Respiratory and metabolic acidosis correction with the ADVanced Organ Support system.Intensive care medicine experimental · 2019Article
- Extracorporeal carbon dioxide removal for acute hypercapnic respiratory failure.Annals of intensive care · 2019Review
- Control of respiratory drive by extracorporeal COCritical care (London, England) · 2019Article
- Modification of Nutrition Therapy During Continuous Renal Replacement Therapy in Critically Ill Pediatric Patients: A Narrative Review and Recommendations.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCritically ill patients with acute respiratory distress syndrome and acute exacerbations of chronic obstructive pulmonary disease often develop hypercapnia and require mechanical ventilation. Extracorporeal carbon dioxide removal can manage hypercarbia by removing carbon dioxide directly from the bloodstream. Respiratory hemodialysis uses traditional hemodialysis to remove CO
methodsBench studies were performed using a scaled down respiratory hemodialyzer in bovine or porcine blood. The scaling factor for the bench top experiments was 22.5. In vitro dialysate flow rates ranged from 2.2 to 24 mL/min (49.5-540 mL/min scaled up) and blood flow rates were set at 11 and 18.7 mL/min (248-421 mL/min scaled up). Blood inlet CO
resultsResults are reported as scaled up values. The CO
conclusionsWhen the bench top data is scaled up, the system removes a therapeutic amount of CO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.