Evidence map›Paper›PMID 28390014›Full record

ReviewWorld journal of microbiology & biotechnology2017

Three, two, one yeast fatty acid desaturases: regulation and function.

Rosa Santomartino, Lina Riego-Ruiz, Michele M Bianchi

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Engineering yeast for tailored fatty acid profiles.Applied microbiology and biotechnology · 2025
    Review
  2. Article
  3. Article
  4. Light Stress in Yeasts: Signaling and Responses in Creatures of the Night.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Rosa SantomartinoDip. di Biologia e Biotecnologie C. Darwin, Sapienza Università di Roma, p.le Aldo Moro 5, 00185, Rome, Italy.
Lina Riego-RuizDivisión de Biología Molecular, Instituto Potosino de Investigación Científica y Tecnológica (IPICYT), A.C., San Luis Potosí, Mexico.
Michele M BianchiDip. di Biologia e Biotecnologie C. Darwin, Sapienza Università di Roma, p.le Aldo Moro 5, 00185, Rome, Italy. michele.bianchi@uniroma1.it.ORCID http://orcid.org/0000-0003-0876-8770
Sapienza University of Rome · ITInstitute for Scientific and Technological Research · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fatty acid composition of biological membranes functionally adapts to environmental conditions by changing its composition through the activity of lipid biosynthetic enzymes, including the fatty acid desaturases. Three major desaturases are present in yeasts, responsible for the generation of double bonds in position C9-C10, C12-C13 and C15-C16 of the carbon backbone. In this review, we will report data addressed to define the functional role of basidiomycete and ascomycete yeast desaturase enzymes in response to various external signals and the regulation of the expression of their corresponding genes. Many yeast species have the complete set of three desaturases; however, only the Δ9 desaturase seems to be necessary and sufficient to ensure yeast viability. The evolutionary issue of this observation will be discussed.

Indexed as

AscomycotaBasidiomycotaEvolution, MolecularFatty Acid DesaturasesFungal ProteinsGene Expression Regulation, FungalGenes, EssentialMicrobial ViabilityMutationPhylogenyFatty Acid DesaturasesFungal ProteinsEvolutionLipid biosynthesisMembranesUnsaturated fatty acids

Identifiers

PMID28390014
OpenAlexW2604264990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.