Evidence map›Paper›PMID 28389987›Full record

ReviewClinical rheumatology2017

"Hiker's feet": a novel cutaneous finding in the inflammatory myopathies.

Jacob T Cox, David M Gullotti, Christopher A Mecoli, Arash H Lahouti, Jemima Albayda, Julie Paik, Cheilonda Johnson, Sonye K Danoff, Andrew L Mammen, Lisa Christopher-Stine

Open access · greenAbstract readReview
In one paragraph

Review in Clinical rheumatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. A Review of Antisynthetase Syndrome-Associated Interstitial Lung Disease.International journal of molecular sciences · 2024
    Review
  7. Mechanic's Feet (Hiker's Feet) in Anti-Synthetase Syndrome.Mediterranean journal of rheumatology · 2024
    Article
  8. Article
  9. Hiker's Feet: Hidden Warning Skin Sign.Internal medicine (Tokyo, Japan) · 2022
    Article
  10. Review
  11. Hiker's feet.Clinical rheumatology · 2022
    Article
  12. Antisynthetase syndrome: A distinct disease spectrum.Journal of scleroderma and related disorders · 2020
    Review
  13. Review
  14. [Antisynthetase syndromes].Zeitschrift fur Rheumatologie · 2019
    Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Cutaneous Manifestations of Dermatomyositis: a Comprehensive Review.Clinical reviews in allergy & immunology · 2017
    Review
  20. Mechanic's hands and hiker's feet in antisynthetase syndrome.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jacob T CoxDepartment of Medicine; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
David M GullottiDepartment of Medicine; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Christopher A MecoliDepartment of Medicine; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Arash H LahoutiDepartment of Medicine; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jemima AlbaydaDepartment of Medicine; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Julie PaikDepartment of Medicine; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Cheilonda JohnsonDepartment of Medicine, Division of Pulmonology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Sonye K DanoffDepartment of Medicine, Division of Pulmonology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Andrew L MammenDepartment of Medicine; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Lisa Christopher-StineDepartment of Medicine; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. lchrist4@jhmi.edu.
Johns Hopkins University · USJohns Hopkins Medicine · USJohns Hopkins Bayview Medical Center · US

Funding

Clinical Support Services for the NIAMS Intramural Research ProgramZIDAR041180 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI COLBERT, ROBERT · 2009 to 2025
$119.2M
Muscle Disease UnitZIAAR041203 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI MAMMEN, ANDREW · 2015 to 2025
$19.7M
Multidisciplinary Rheumatology Training ProgramT32AR048522 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI CLIFTON O BINGHAM, LIVIA A CASCIOLA-ROSEN · 2003 to 2026
$6.4M
NIAMS NIH HHS T32 AR048522
6 · The paper itself

Abstract

Mechanic's hands is a well-characterized manifestation of select idiopathic inflammatory myopathy (IIM) syndromes. Less well characterized is the hyperkeratosis of the toes and plantar surface of the feet that can also accompany these disorders. We aim to describe common pedal signs in the context of IIM, and suggest that it may be another key feature in the presentation of these syndromes. A cohort of 2145 myositis patient charts gathered since 2003 were retrospectively reviewed using the key search terms "mechanic's feet" and/or "mechanic's foot." Charts that included either phrase were further reviewed for clinical characteristics. Nine patients were identified with documentation describing "mechanic's feet" or "mechanic's foot." All nine affected individuals carried a diagnosis of DM, seven of whom also met criteria for antisynthetase syndrome. In eight patients (89%), it presented in conjunction with mechanic's hands. Six (67%) presented with anti-Jo-1 antibodies, and three (33%) were seronegative. Although the term "mechanic's feet" has been used to describe this clinical finding in patients in our myositis cohort, we propose the term "hiker's feet," given that the presentation resembles a callousing pattern more typical of avid hikers or long-distance walkers. Prevalence data are not yet known but should be considered for further study. If the presenting signs of IIM are expanded to include hiker's feet, it could aid in not only diagnosis and management but also provide insights into the pathophysiology of these diseases.

Indexed as

AdultDermatomyositisFemaleHumansMaleMiddle AgedMyositisAntisynthetase syndromeDermatomyositisHyprkeratosisMechanics handsMyositis

Identifiers

PMID28389987
PMCPMC6100725
OpenAlexW2604309799

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.