ArticleJournal of bone and mineral metabolism2018
Effect of radiation dose reduction on texture measures of trabecular bone microstructure: an in vitro study.
Article in Journal of bone and mineral metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Computed tomography with low-dose radiation versus standard-dose radiation for diagnosing fractures: systematic review and meta-analysis.Sao Paulo medical journal = Revista paulista de medicinaPooled it
- Assessment of Radiographic Image Texture in the Maxilla and Mandible Around Titanium Inserts Used for Osteosynthesis of Dentofacial Deformities.Journal of functional biomaterials · 2025Article
- The Application of Advanced Bone Imaging Technologies in Sports Medicine.Radiology research and practice · 2023Review
- Multi-detector computed tomography (MDCT) imaging: association of bone texture parameters with finite element analysis (FEA)-based failure load of single vertebrae and functional spinal units.Quantitative imaging in medicine and surgery · 2021Article
- Gender-, Age- and Region-Specific Characterization of Vertebral Bone Microstructure Through Automated Segmentation and 3D Texture Analysis of Routine Abdominal CT.Frontiers in endocrinology · 2021Article
- Image Processing-Based Detection of Pipe Corrosion Using Texture Analysis and Metaheuristic-Optimized Machine Learning Approach.Computational intelligence and neuroscience · 2019Article
- Feasibility of opportunistic osteoporosis screening in routine contrast-enhanced multi detector computed tomography (MDCT) using texture analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Osteoporosis is characterized by bone loss and degradation of bone microstructure leading to fracture particularly in elderly people. Osteoporotic bone degeneration and fracture risk can be assessed by bone mineral density and trabecular bone score from 2D projection dual-energy X-ray absorptiometry images. However, multidetector computed tomography image based quantification of trabecular bone microstructure showed significant improvement in prediction of fracture risk beyond that from bone mineral density and trabecular bone score; however, high radiation exposure limits its use in routine clinical in vivo examinations. Hence, this study investigated reduction of radiation dose and its effects on image quality of thoracic midvertebral specimens. Twenty-four texture features were extracted to quantify the image quality from multidetector computed tomography images of 11 thoracic midvertebral specimens, by means of statistical moments, the gray-level co-occurrence matrix, and the gray-level run-length matrix, and were analyzed by an independent sample t-test to observe differences in image texture with respect to radiation doses of 80, 150, 220, and 500 mAs. The results showed that three features-namely, global variance, energy, and run percentage, were not statistically significant ([Formula: see text]) for low doses with respect to 500 mAs. Hence, it is evident that these three dose-independent features can be used for disease monitoring with a low-dose imaging protocol.
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Registered trials
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