Evidence map›Paper›PMID 28389904›Full record

ArticleFish physiology and biochemistry2017

Cylindrospermopsin effects on cell viability and redox milieu of Neotropical fish Hoplias malabaricus hepatocytes.

R C Silva, S Liebel, H H P de Oliveira, W A Ramsdorf, J R E Garcia, S M F O Azevedo, V F Magalhães, C A Oliveira Ribeiro, F Filipak Neto

Abstract read
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In one paragraph

Article in Fish physiology and biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

R C SilvaInstituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Bloco G, Ilha do Fundão, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21949-900, Brazil.
S LiebelDepartamento de Biologia Celular, Universidade Federal do Paraná, Cx. Postal 19031, Curitiba, PR, 81531-990, Brazil.
H H P de OliveiraDepartamento de Biologia Celular, Universidade Federal do Paraná, Cx. Postal 19031, Curitiba, PR, 81531-990, Brazil.
W A RamsdorfDepartamento de Genética, Universidade Federal do Paraná, Caixa Postal 19031, Curitiba, PR, 81531-990, Brazil.
J R E GarciaCampus Laranjeiras do Sul, Universidade Federal da Fronteira Sul, Laranjeiras do Sul, PR, 85303-775, Brazil.
S M F O AzevedoInstituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Bloco G, Ilha do Fundão, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21949-900, Brazil.
V F MagalhãesInstituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Bloco G, Ilha do Fundão, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21949-900, Brazil. valeria@biof.ufrj.br.
C A Oliveira RibeiroDepartamento de Biologia Celular, Universidade Federal do Paraná, Cx. Postal 19031, Curitiba, PR, 81531-990, Brazil. ciro@ufpr.br.
F Filipak NetoDepartamento de Biologia Celular, Universidade Federal do Paraná, Cx. Postal 19031, Curitiba, PR, 81531-990, Brazil.
Universidade Federal do Paraná · BRUniversidade Federal do Rio de Janeiro · BRUniversidade Estadual de Ponta Grossa · BRUniversidade Federal da Fronteira Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cylindrospermopsin (CYN) is a cyanotoxin that is cytotoxic to a wide variety of cells, particularly to the hepatocytes. In this study, the toxic effects of purified CYN were investigated in primary cultured hepatocytes of Neotropical fish Hoplias malabaricus. After isolation, attachment, and recovery for 72 h, the cells were exposed for 72 h to 0, 0.1, 1.0, 10, and 100 μg l

Indexed as

CharaciformesAlkaloidsAnimalsBacterial ToxinsBiomarkersCells, CulturedCell SurvivalCyanobacteria ToxinsDose-Response Relationship, DrugHepatocytesOxidative StressUracilAlkaloidsBacterial ToxinsBiomarkersCyanobacteria ToxinscylindrospermopsinUracilCyanotoxinEffectsIn vitroNeotropical fishOxidative stress

Identifiers

PMID28389904
OpenAlexW2605139748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.