Evidence map›Paper›PMID 28389843›Full record

ReviewCurrent allergy and asthma reports2017

Impact of Respiratory Virus Infections in Exacerbation of Acute and Chronic Rhinosinusitis.

Kai Sen Tan, Yan Yan, Hsiao Hui Ong, Vincent T K Chow, Li Shi, De-Yun Wang

Open access · bronzeAbstract readReview
In one paragraph

Review in Current allergy and asthma reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 66 citations in OpenAlex.

  1. Trial
  2. The role of virus in nasal inflammation.European journal of medical research · 2025
    Review
  3. Acute Exacerbations of Chronic Rhinosinusitis.Current allergy and asthma reports · 2025
    Review
  4. Article
  5. Viruses in bronchiectasis.ERJ open research · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Pediatric chronic rhinosinusitis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. The Role of Viruses in the Inception of Chronic Rhinosinusitis.Clinical and experimental otorhinolaryngology · 2022
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Kai Sen TanDepartment of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore, 119228, Singapore.
Yan YanDepartment of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore, 119228, Singapore.
Hsiao Hui OngDepartment of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore, 119228, Singapore.
Vincent T K ChowDepartment of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Li ShiDepartment of Otolaryngology, The Second Hospital of Shandong University, Jinan, China.
De-Yun WangDepartment of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore, 119228, Singapore. entwdy@nus.edu.sg.
National University of Singapore · SGSecond Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rhinosinusitis (RS) is a symptomatic disease classification of many causes and is a major economic burden worldwide. It is widely accepted that RS is further classified into acute (ARS) and chronic (CRS) rhinosinusitis based on the duration of the symptoms, and that viral infection plays a large role in initiating or potentiating the disease. In this review, we examine the role of respiratory virus infection in the exacerbation of ARS and CRS. We explore the epidemiology of viral exacerbation of ARS and CRS and highlight key viruses that may cause exacerbation. We also review the current understanding of viral infections in the upper airway to further explain the putative underlying mechanisms of inflammatory events in ARS and CRS exacerbation. Advances in accurate diagnosis of the etiologic respiratory viruses of ARS and CRS symptoms which can lead to better disease management are also surveyed. In addition to the current treatments which provide symptomatic relief, we also explore the potential of harnessing existing antiviral strategies to prevent ARS and CRS exacerbation, especially with improved viral diagnostic tools to guide accurate prescription of antivirals against causative respiratory viruses.

Indexed as

Antiviral AgentsChronic DiseaseDisease ManagementHumansRespiratory Tract InfectionsRhinitisSinusitisVirus DiseasesAntiviral AgentsAcute rhinosinusitisAntiviralsBacterial infectionChronic rhinosinusitisDiagnosisExacerbationTreatmentViral infection

Identifiers

PMID28389843
PMCPMC7088794
OpenAlexW2604714695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.