ArticleInternational journal of colorectal disease2017
Poor prognosis of young patients with colorectal cancer: a retrospective study.
Article in International journal of colorectal disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A comparison of overall survival from early-onset and late-onset colorectal cancer stratified by TNM stage: a systematic review.British journal of cancer · 2026Pooled it
- Red Flag Signs and Symptoms for Patients With Early-Onset Colorectal Cancer: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- The impact of age on survival in stage II colon cancer: a SEER database analysis stratified by chemotherapy status.Translational cancer research · 2026Article
- Article
- A retrospective analysis of key predictors and patient outcomes: Using artificial intelligence for precision survival prediction in colorectal cancer.German medical science : GMS e-journal · 2025Article
- Younger patients with colorectal cancer may have better long-term survival after surgery: a retrospective study based on propensity score matching analysis.World journal of surgical oncology · 2024Article
- Nomograms for predicting overall survival in colorectal cancer patients with metastasis to the liver, lung, bone, and brain.Cancer causes & control : CCC · 2023Article
- Effects of LINC00261 targeting miR-148a/WNT10b axis on the proliferation and apoptosis of colorectal cancer cells.Heliyon · 2023Article
- Early Onset Metastatic Colorectal Cancer: Current Insights and Clinical Management of a Rising Condition.Cancers · 2023Review
- A Retrospective Multicenter Study of the Clinicopathological Characteristics and Prognosis of Young Adult Patients with Colorectal Cancer: Effects of Chemotherapy on Prognosis.Journal of clinical medicine · 2023Article
- Risk factors of lymph node metastasis in patients with T1 stage colorectal cancer-a retrospective cohort study based on the Surveillance, Epidemiology, and End Results database.Journal of gastrointestinal oncology · 2023Article
- Correlation between mismatch repair statuses and the prognosis of stage I-IV colorectal cancer.Frontiers in oncology · 2023Article
- Effect of age on the prognosis of intrahepatic cholangiocarcinoma.The Korean journal of internal medicine · 2023Article
- Prognostic factors for disease-free survival in postoperative patients with hepatocellular carcinoma and construction of a nomogram model.World journal of clinical cases · 2022Article
- The short-term and oncologic outcomes of younger VS older colorectal cancer patients undergoing primary surgery: a propensity score matching analysis.BMC cancer · 2022Article
- A comparative analysis of the clinicopathological profile of early-onset versus late-onset rectal cancer patients.Ecancermedicalscience · 2022Article
- Epidemiology and Outcomes of Young-Onset Esophageal Adenocarcinoma: An Analysis from a Population-Based Database.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021Article
- Sporadic colorectal cancer in adolescents and young adults: a scoping review of a growing healthcare concern.International journal of colorectal disease · 2020Article
- Clinicopathological features and survival of colorectal cancer patients younger than 50 years: a retrospective comparative study.Journal of the Egyptian National Cancer Institute · 2019Article
- Early-onset colorectal cancer in young individuals.Molecular oncology · 2019Review
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7 authors.
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Abstract
purposeThe present study aimed to explore the survival outcomes of patients with colorectal cancer (CRC) aged 35 years and younger.
methodsThis retrospective cohort study included a total of 995 patients with CRC treated between January 2003 and September 2011. The patients were assorted into the young (aged 18-35 years) and older (aged 36-75 years) groups. The clinical characteristics and survival outcomes of the patients in the young group were compared with those of the patients in the older group for evaluation.
resultsCompared with the older group, a significantly higher number of patients in the young group had right-sided colon cancer (30.9 vs. 19.6%, P = 0.026), high histologic grade tumor (14.7 vs. 6.4%, P = 0.021), and stage III disease (50.0 vs. 35.5%, P = 0.016). In stage III disease, compared with the older group, the patients in the young group had worse survival outcome in terms of 5-year overall survival (OS, P = 0.007), cancer-specific survival (CSS, P = 0.010), and disease-free survival (DFS, P = 0.039). Multivariate analysis revealed that age ≤35 years was an independent risk factor in terms of 5-year OS (hazard ratio [HR] = 1.68; 95% confidence interval [CI]: 1.12-2.54; P = 0.012), CSS (HR = 1.74; 95% CI: 1.15-2.65; P = 0.009), and DFS (HR = 1.58; 95% CI: 1.06-2.35; P = 0.024).
conclusionsThe young patients with CRC aged 35 years and younger had worse prognosis compared with older patients, especially for stage III disease.
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