Evidence map›Paper›PMID 28389566›Full record

ReviewThe Journal of biological chemistry2017

Microbial metabolites in health and disease: Navigating the unknown in search of function.

Kristina B Martinez, Vanessa Leone, Eugene B Chang

Abstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Metabolomic signaling in sarcoidosis pathogenesis.Current opinion in immunology · 2026
    Review
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kristina B MartinezFrom the Department of Medicine, Knapp Center for Biomedical Discovery, University of Chicago, Chicago, Illinois 60637.
Vanessa LeoneFrom the Department of Medicine, Knapp Center for Biomedical Discovery, University of Chicago, Chicago, Illinois 60637.
Eugene B ChangFrom the Department of Medicine, Knapp Center for Biomedical Discovery, University of Chicago, Chicago, Illinois 60637 echang@medicine.bsd.uchicago.edu.

Funding

ULTRASTRUCTURE AND CYTOMORPHOLOGY COREP30DK042086 · NIDDK · UNIVERSITY OF CHICAGO · PI LIU, CAMBRIAN YANGSHAO · 1990 to 2025
$29.8M
Dietary fat effects on gut microbes, host immune state and experimental colitisR01DK097268 · NIDDK · UNIVERSITY OF CHICAGO · PI CHANG, EUGENE B · 2012 to 2016
$2.2M
Diet induced obesity from gut microbial disruption of host metabolic networksR56DK102872 · NIDDK · UNIVERSITY OF CHICAGO · PI CHANG, EUGENE B, JONES, DEAN PAUL · 2015 to 2015
$409k
NIDDK NIH HHS P30 DK042086NIDDK NIH HHS R01 DK097268NIDDK NIH HHS R56 DK102872
6 · The paper itself

Abstract

The gut microbiota has been implicated in the development of a number of chronic gastrointestinal and systemic diseases. These include inflammatory bowel diseases, irritable bowel syndrome, and metabolic (

Indexed as

Diabetes MellitusGastrointestinal MicrobiomeHost-Pathogen InteractionsInflammatory Bowel DiseasesIrritable Bowel SyndromeNon-alcoholic Fatty Liver DiseaseObesityAnimalsHumansRNA, BacterialRNA, Ribosomal, 16SRNA, BacterialRNA, Ribosomal, 16Scardiovascular diseaseinflammatory bowel disease (IBD)metabolomicsmetagenomicsmeta-omicsmetatranscriptomicsmicrobial metabolitesmulti-omicsneurological disease

Identifiers

PMID28389566
PMCPMC5448084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.