Evidence map›Paper›PMID 28389542›Full record

ArticleApplied and environmental microbiology2017

Five Fatty Aldehyde Dehydrogenase Enzymes from Marinobacter and Acinetobacter spp. and Structural Insights into the Aldehyde Binding Pocket.

Jonathan H Bertram, Kalene M Mulliner, Ke Shi, Mary H Plunkett, Peter Nixon, Nicholas A Serratore, Christopher J Douglas, Hideki Aihara, Brett M Barney

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Development of a Genetic System forFrontiers in microbiology · 2018
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jonathan H BertramDepartment of Bioproducts and Biosystems Engineering, University of Minnesota, St. Paul, Minnesota, USA.
Kalene M MullinerDepartment of Bioproducts and Biosystems Engineering, University of Minnesota, St. Paul, Minnesota, USA.
Ke ShiDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.
Mary H PlunkettBiotechnology Institute, University of Minnesota, St. Paul, Minnesota, USA.
Peter NixonDepartment of Bioproducts and Biosystems Engineering, University of Minnesota, St. Paul, Minnesota, USA.
Nicholas A SerratoreDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA.
Christopher J DouglasDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA.
Hideki AiharaDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.
Brett M BarneyDepartment of Bioproducts and Biosystems Engineering, University of Minnesota, St. Paul, Minnesota, USA bbarney@umn.edu.
University of Minnesota · USBiotechnology Institute · US

Funding

Overall EvaluationP41GM103403 · NIGMS · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2012 to 2017
$14.3M
Structural studies of viral replication and invasionR35GM118047 · NIGMS · UNIVERSITY OF MINNESOTA · PI Hideki Aihara · 2016 to 2026
$6.3M
Pixel Array Detector for X-ray CrystallographyS10RR029205 · NCRR · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2010 to 2010
$1.8M
NCRR NIH HHS S10 RR029205NIGMS NIH HHS P41 GM103403NIGMS NIH HHS R35 GM118047
6 · The paper itself

Abstract

Enzymes involved in lipid biosynthesis and metabolism play an important role in energy conversion and storage and in the function of structural components such as cell membranes. The fatty aldehyde dehydrogenase (FAldDH) plays a central function in the metabolism of lipid intermediates, oxidizing fatty aldehydes to the corresponding fatty acid and competing with pathways that would further reduce the fatty aldehydes to fatty alcohols or require the fatty aldehydes to produce alkanes. In this report, the genes for four putative FAldDH enzymes from

Indexed as

AcinetobacterAldehyde OxidoreductasesAldehydesAmino Acid SequenceBacterial ProteinsBinding SitesKineticsMarinobacterModels, MolecularMolecular Sequence DataPhylogenySequence AlignmentSubstrate SpecificityAldehyde OxidoreductasesAldehydesBacterial Proteinslong-chain-aldehyde dehydrogenasedecanallipid biosynthesisMaqu_3316Marinobacterwax ester

Identifiers

PMID28389542
PMCPMC5452803
OpenAlexW2604797261

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.