ReviewCold Spring Harbor perspectives in medicine2017
The Role of MicroRNAs in the Cardiac Response to Exercise.
Review in Cold Spring Harbor perspectives in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- miR-26b-5p responds to aerobic exercise intervention for concussion recovery in adolescent athletes: a pilot trial.Brain injury · 2026Article
- Swimming is superior to running in inducing physiological cardiac hypertrophy and enhancing myocardial performance.Scientific reports · 2026Article
- MicroRNA, MicroRNA-lncRNA and MicroRNA-Circular RNA axes, and exosomal MicroRNAs: driving exercise-induced cardioprotection in heart failure.Frontiers in cell and developmental biology · 2026Review
- Multi-Omics Deciphers Divergent Mechanisms in Differentially Cardiac-Remodeled Yili Horses Under Conditions of Equivalent Power Output.Animals : an open access journal from MDPI · 2025Article
- Athlete's Heart Revisited: Historical, Clinical, and Molecular Perspectives.Circulation research · 2025Review
- Molecular Mediators of the Cardiac Benefits of Exercise.Circulation research · 2025Review
- Regulating the expression of exercise-induced micro-RNAs and long non-coding RNAs: implications for controlling cardiovascular diseases and heart failure.Frontiers in molecular biosciences · 2025Review
- Resistance training and cardiovascular health: epigenetic regulation.Frontiers in physiology · 2025Review
- Is It Possible to Train the Endothelium?-A Narrative Literature Review.Life (Basel, Switzerland) · 2024Review
- Exercise Training-Induced MicroRNA Alterations with Protective Effects in Cardiovascular Diseases.Reviews in cardiovascular medicine · 2023Review
- Beyond cardiomyocytes: Cellular diversity in the heart's response to exercise.Journal of sport and health science · 2023Review
- MicroRNAs as biomarkers for monitoring cardiovascular changes in Type II Diabetes Mellitus (T2DM) and exercise.Journal of diabetes and metabolic disorders · 2022Review
- The genetics of human performance.Nature reviews. Genetics · 2022Review
- Exercise Mediates Heart Protection via Non-coding RNAs.Frontiers in cell and developmental biology · 2020Review
- Circulating microRNAs in Response to Exercise Training in Healthy Adults.Frontiers in genetics · 2020Article
- Review
- Specific circulating microRNAs display dose-dependent responses to variable intensity and duration of endurance exercise.American journal of physiology. Heart and circulatory physiology · 2018Article
- Free Circulating miRNAs Measurement in Clinical Settings: The Still Unsolved Issue of the Normalization.Advances in clinical chemistryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Noncoding microRNAs (miRNAs) have emerged as central regulators of cardiac biology, modulating cardiac development and the response to pathological stress in disease. Although less well developed, emerging evidence suggests miRNAs are likely also important in the heart's response to the physiological stress of exercise. Given the well-recognized cardiovascular benefits of exercise, elucidating the contribution of miRNAs to this response has the potential not only to reveal novel aspects of cardiovascular biology but also to identify new targets for therapeutic intervention that may complement those discovered through studies of diseased hearts. Here, we first provide an overview of the cardiovascular effects of exercise as well as some of the major protein signaling mechanisms contributing to these effects. We then review the evidence that both cardiac and circulating miRNAs are dynamically regulated by exercise and regulate these mechanisms and phenotypes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.