ArticleAmerican journal of obstetrics and gynecology2017
Cesarean delivery in the second stage of labor and the risk of subsequent premature birth.
Article in American journal of obstetrics and gynecology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 91 citations in OpenAlex.
- Instruments for assisted vaginal birth.The Cochrane database of systematic reviews · 2021Pooled it
- The use of specialised preterm birth clinics for women at high risk of spontaneous preterm birth: a systematic review.BMC pregnancy and childbirth · 2020Pooled it
- Prediction of preterm birth using 3D volume cesarean scar morphology in pregnant women with previous advanced labor cesarean delivery.Acta obstetricia et gynecologica Scandinavica · 2026Observational
- Risk of recurrent spontaneous preterm birth following preterm full dilatation cesarean delivery.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Uterine closure after cesarean delivery: surgical technique, biological rationale, and clinical implications.American journal of obstetrics and gynecology · 2026Review
- Risk of Spontaneous Preterm Birth in a Subsequent Pregnancy After Full Dilatation Caesarean Birth: A Nationwide Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Escalating caesarean deliveries and the impact on subsequent preterm birth.European journal of obstetrics & gynecology and reproductive biology: X · 2025Review
- Three-Dimensional Volume Ultrasound Assessment of Cesarean Scar Niche and Cervix in Pregnant Women: A Reproducibility Study.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025Article
- Associations between term cesarean delivery in the first pregnancy and second-pregnancy preterm delivery.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Evaluating pregnancy outcomes in women with uterine fibroids treated with high-intensity focused ultrasound: insights from a single-institution study.Reproductive health · 2024Article
- Obstetrician views on Fetal Pillow® device use and research in Aotearoa New Zealand: A cross-sectional survey.The Australian & New Zealand journal of obstetrics & gynaecology · 2024Article
- Cesarean section at full dilatation in the first birth is not associated with an increased risk of subsequent miscarriage: A historical cohort study.Acta obstetricia et gynecologica Scandinavica · 2024Article
- Engaging women to set the research agenda for assisted vaginal birth.Health expectations : an international journal of public participation in health care and health policy · 2024Article
- The use of bubble charts in analyzing the global second-stage cesarean delivery rates: a systematic review.AJOG global reports · 2024Review
- Cesarean Uterine Lacerations and Prematurity in the Following Delivery: A Retrospective Longitudinal Follow-Up Cohort Study.Journal of clinical medicine · 2024Article
- Risk of Preterm Birth among Secundiparas with a Previous Cesarean due to a Failed Vacuum Delivery.Journal of clinical medicine · 2023Article
- A research agenda to improve incidence and outcomes of assisted vaginal birth.Bulletin of the World Health Organization · 2023Article
- Reproducibility of assessment of full-dilatation Cesarean section scar in women undergoing second-trimester screening for preterm birth.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2022Article
- Prediction of Emergency Cesarean Section Using Machine Learning Methods: Development and External Validation of a Nationwide Multicenter Dataset in Republic of Korea.Life (Basel, Switzerland) · 2022Article
- Thyroid Laboratory Testing and Management in Women on Thyroid Replacement Before Pregnancy and Associated Pregnancy Outcomes.Thyroid : official journal of the American Thyroid Association · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCesarean delivery is being increasingly used by obstetricians for indicated deliveries in the second stage of labor. Unplanned extension of the uterine incision involving the cervix often occurs with these surgeries. Therefore, we hypothesized that cesarean delivery in the second stage of labor may increase the rate of subsequent spontaneous premature birth.
objectiveWe sought to determine if cesarean delivery in the late first stage of labor or in the second stage of labor increases the risk of a subsequent spontaneous preterm birth. STUDY
designWe conducted a retrospective cohort study of matched first and second births from a large Canadian perinatal database. The primary outcomes were spontaneous premature birth <37 and <32 weeks of gestation in the second birth. The exposure was stage of labor and cervical dilation at the time of the first cesarean delivery. The protocol and analysis plan was registered prior to obtaining data at Open Science Foundation.
resultsIn total, 189,021 paired first and second births were identified. The risk of spontaneous preterm delivery <37 and <32 weeks of gestation in the second birth was increased when the first birth was by cesarean delivery in the second stage of labor (relative risk, 1.57; 95% confidence interval, 1.43-1.73 and relative risk, 2.12; 95% confidence interval, 1.67-2.68, respectively). The risk of perinatal death in the second birth, excluding congenital anomalies, was also correspondingly increased (relative risk, 1.44; 95% confidence interval, 1.05-1.96).
conclusionCesarean delivery in second stage of labor was associated with a 2-fold increase in the risk of spontaneous preterm birth <32 weeks of gestation in a subsequent birth. This information may inform management of operative delivery in the second stage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.