ArticleEBioMedicine2017
Clock Gene Dysregulation Induced by Chronic ER Stress Disrupts β-cell Function.
Open access · goldAbstract read
In one paragraph
Article in EBioMedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- D-Box Binding Protein (DBP) as a Circadian Output Regulator: Molecular Mechanisms, Tissue-Specific Functions, and Disease Relevance.International journal of molecular sciences · 2026Review
- Genetically encoded manipulation of ATP/ADP ratio in human cells uncovers proteomic and physiological signatures of energy stress.Cell chemical biology · 2026Article
- Noncanonical clock regulators control stress responses in digestive diseases.Trends in endocrinology and metabolism: TEM · 2026Review
- Integrative multi-omics analysis of metabolic dysregulation induced by occupational benzene exposure in mice.The Science of the total environment · 2025Article
- The roles of output clock genes in regulating glucose metabolism.Journal of diabetes investigation · 2024Article
- E4BP4 in macrophages induces an anti-inflammatory phenotype that ameliorates the severity of colitis.Communications biology · 2024Article
- The role of basic leucine zipper transcription factor E4BP4 in cancer: a review and update.Molecular biology reports · 2024Review
- A new border for circadian rhythm gene NFIL3 in diverse fields of cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023Review
- Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes.Nature genetics · 2023Article
- Integration of single-cell multiomic measurements across disease states with genetics identifies mechanisms of beta cell dysfunction in type 2 diabetes.bioRxiv : the preprint server for biology · 2023Article
- Feeding-induced hepatokines and crosstalk with multi-organ: A novel therapeutic target for Type 2 diabetes.Frontiers in endocrinology · 2023Review
- Metabolic state switches between morning and evening in association with circadian clock in people without diabetes.Journal of diabetes investigation · 2022Article
- Wolframin deficiency is accompanied with metabolic inflexibility in rat striated muscles.Biochemistry and biophysics reports · 2022Article
- The circadian clock and metabolic homeostasis: entangled networks.Cellular and molecular life sciences : CMLS · 2021Review
- Single-Cell Transcriptional Profiling of Mouse Islets Following Short-Term Obesogenic Dietary Intervention.Metabolites · 2020Article
- Hepatic E4BP4 induction promotes lipid accumulation by suppressing AMPK signaling in response to chemical or diet-induced ER stress.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020Article
- Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver.Molecular systems biology · 2020Article
- CLOCK disruption aggravates carotid artery stenosis through endoplasmic reticulum stress-induced endothelial-mesenchymal transition.American journal of translational research · 2020Article
- Calcium Signaling and Contractility in Cardiac Myocyte of Wolframin Deficient Rats.Frontiers in physiology · 2019Article
- The Influence of Short-term Fasting on Muscle Growth and Fiber Hypotrophy Regulated by the Rhythmic Expression of Clock Genes and Myogenic Factors in Nile Tilapia.Marine biotechnology (New York, N.Y.) · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Yasuharu OhtaDepartment of Endocrinology, Metabolism, Hematological Science and Therapeutics, Yamaguchi University, Graduate School of Medicine, 1-1-1, Minami Kogushi, Ube, Yamaguchi 755-8505, Japan; Department of Diabetes Research, Yamaguchi University, School of Medicine, 1-1-1, Minami Kogushi, Ube, Yamaguchi 755-8505, Japan. Electronic address: yohta@yamaguchi-u.ac.jp.
Akihiko TaguchiDepartment of Endocrinology, Metabolism, Hematological Science and Therapeutics, Yamaguchi University, Graduate School of Medicine, 1-1-1, Minami Kogushi, Ube, Yamaguchi 755-8505, Japan.
Takuro MatsumuraDepartment of Endocrinology, Metabolism, Hematological Science and Therapeutics, Yamaguchi University, Graduate School of Medicine, 1-1-1, Minami Kogushi, Ube, Yamaguchi 755-8505, Japan.
Hiroko NakabayashiDepartment of Endocrinology, Metabolism, Hematological Science and Therapeutics, Yamaguchi University, Graduate School of Medicine, 1-1-1, Minami Kogushi, Ube, Yamaguchi 755-8505, Japan.
Masaru AkiyamaDepartment of Endocrinology, Metabolism, Hematological Science and Therapeutics, Yamaguchi University, Graduate School of Medicine, 1-1-1, Minami Kogushi, Ube, Yamaguchi 755-8505, Japan.
Kaoru YamamotoDepartment of Endocrinology, Metabolism, Hematological Science and Therapeutics, Yamaguchi University, Graduate School of Medicine, 1-1-1, Minami Kogushi, Ube, Yamaguchi 755-8505, Japan.
Ruriko FujimotoDepartment of Endocrinology, Metabolism, Hematological Science and Therapeutics, Yamaguchi University, Graduate School of Medicine, 1-1-1, Minami Kogushi, Ube, Yamaguchi 755-8505, Japan.
Risa SuetomiDepartment of Endocrinology, Metabolism, Hematological Science and Therapeutics, Yamaguchi University, Graduate School of Medicine, 1-1-1, Minami Kogushi, Ube, Yamaguchi 755-8505, Japan.
Akie YanaiDepartment of Neuroanatomy, Yamaguchi University, Graduate School of Medicine, 1-1-1, Minami Kogushi, Ube, Yamaguchi 755-8505, Japan.
Koh ShinodaDepartment of Neuroanatomy, Yamaguchi University, Graduate School of Medicine, 1-1-1, Minami Kogushi, Ube, Yamaguchi 755-8505, Japan.
Yukio TanizawaDepartment of Endocrinology, Metabolism, Hematological Science and Therapeutics, Yamaguchi University, Graduate School of Medicine, 1-1-1, Minami Kogushi, Ube, Yamaguchi 755-8505, Japan. Electronic address: tanizawa@yamaguchi-u.ac.jp.
Yamaguchi University · JP
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Wfs1
Indexed as
Endoplasmic Reticulum StressAnimalsBasic-Leucine Zipper Transcription FactorsCalciumCell LineCLOCK ProteinsDNA-Binding ProteinsGlucose Tolerance TestHumansInsulinInsulin-Secreting CellsInsulin SecretionMaleMembrane ProteinsMiceMice, TransgenicBasic-Leucine Zipper Transcription FactorsCalciumCLOCK protein, humanCLOCK ProteinsDBP protein, humanDNA-Binding ProteinsIns1 protein, mouseInsulinMembrane ProteinsNFIL3 protein, humanTranscription Factorswolframin proteinClock out-put geneDiabetes mellitusEndoplasmic reticulum stressInsulin secretionPancreatic islet β-cell
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What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.