Evidence map›Paper›PMID 28388942›Full record

Trial reportBMC gastroenterology2017

Costs and quality of life of small-incision open cholecystectomy and laparoscopic cholecystectomy - an expertise-based randomised controlled trial.

Mats H Rosenmüller, Erik Nilsson, Fredrik Lindberg, Sten-Olof Åberg, Markku M Haapamäki

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00370344 (An Expertise-based Randomized Controlled Trial Comparing Minilaparotomy Cholecystectomy and Laparoscopic Cholecystectomy), which is not on this map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00370344 phase2 / phase3completednot on this map

An Expertise-based Randomized Controlled Trial Comparing Minilaparotomy Cholecystectomy and Laparoscopic Cholecystectomy

TypeinterventionalSponsorUmeå UniversityRan2006 to 2011Enrolled355ConditionsBiliary Tract Diseases, Gallbladder Diseases, Cholecystitis, CholecystolithiasisArmsLaparoscopic cholecystectomy, Small-incision open cholecystectomy
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Reporting of health-related quality of life in emergency laparotomy trials: a systematic review and narrative synthesis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Pooled it
  2. Health-related quality of life among patients with gallstone disease: a systematic review and meta-analysis of EQ-5D utility scores.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Review
  8. Patient reported outcomes in elective laparoscopic cholecystectomy.Annals of hepato-biliary-pancreatic surgery · 2019
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mats H RosenmüllerDepartment of Surgery, Umeå University, SE-901 85, Umeå, Sweden. mats.rosenmuller@surgery.umu.se.
Erik NilssonDepartment of Surgery, Umeå University, SE-901 85, Umeå, Sweden.
Fredrik LindbergDepartment of Surgery, Umeå University, SE-901 85, Umeå, Sweden.
Sten-Olof ÅbergDepartment of Surgery, Umeå University, SE-901 85, Umeå, Sweden.
Markku M HaapamäkiDepartment of Surgery, Umeå University, SE-901 85, Umeå, Sweden.
Umeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealth care providers need solid evidence based data on cost differences between alternative surgical procedures for common surgical disorders. We aimed to compare small-incision open cholecystectomy (SIOC) and laparoscopic cholecystectomy (LC) concerning costs and health-related quality of life using data from an expertise-based randomised controlled trial.

methodsPatients scheduled for cholecystectomy were assigned to undergo LC or SIOC performed by surgeons in two different expert groups. Total costs were calculated in USD. Reusable instruments were assumed for the cost analysis. Quality of life was measured using the EuroQol 5-D 3-L (EQ 5-D-3L), at five postoperative time points and calculated to Area Under Curve (AUC) for 1 year postoperatively. Two hospitals participated in the trial, which included both emergency and elective surgery.

resultsOf 477 patients that underwent a cholecystectomy during the study period, 355 (74.9%) were randomised and 323 analysed, 172 LC and 151 SIOC patients. Both direct and total costs were less for SIOC than for LC patients. The total costs were 5429 (4293-6932) USD for LC and 4636 (3905-5746) USD for SIOC, P = 0.001. The quality of life index did not differ between the LC and SIOC groups at any time. Median values (25th and 75th percentiles (p25-p75)) for AUC at 1 year were as follows: 349 (337-351) for LC and 349 (338-350) for SIOC.

conclusionsIn this expertise-based randomised controlled trial LC was a more costly procedure and quality of life did not differ after SIOC and LC. (ClinicalTrials.gov Identifier: NCT00370344, August 30, 2006).

Indexed as

Health Care CostsQuality of LifeAdolescentAdultAgedAged, 80 and overCholecystectomyCholecystectomy, LaparoscopicCosts and Cost AnalysisFemaleGallbladder DiseasesHumansLaparotomyMaleMiddle AgedProfessional CompetenceHealth care costsMinilaparotomySurgical procedures

Identifiers

PMID28388942
PMCPMC5385047
OpenAlexW2604341199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.