Evidence map›Paper›PMID 28388917›Full record

ReviewJournal of translational medicine2017

Influence of diet on the gut microbiome and implications for human health.

Rasnik K Singh, Hsin-Wen Chang, Di Yan, Kristina M Lee, Derya Ucmak, Kirsten Wong, Michael Abrouk, Benjamin Farahnik, Mio Nakamura, Tian Hao Zhu and 2 more

3 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Journal of translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 1,355 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,355citing papers in PubMed, 8 pooled it
74.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05275608 narecruitingnot on this mapstarted 2022, after this paper: background citation

Effects of Very Low Calorie Ketogenic Diet on Microbiota, Adipose Tissue and Immunitary Regulation: Pilot Study on Patients with Metabolic Syndrome

TypeinterventionalSponsorAzienda Ospedaliero Universitaria Maggiore della CaritaRan2022 to 2025Enrolled40ConditionsDiabetes Mellitus, Type 2, Non-alcoholic Fatty Liver Disease, Obesity, Metabolic SyndromeArmsVLCKD diet with replacing meals, Hypocaloric mediterranean Diet
NCT05627089 withdrawnnot on this mapstarted 2023, after this paper: background citation

Rheumatoid Arthritis and Myositis Cohort

TypeobservationalSponsorAttune Health Research, Inc.Ran2023 to 2035Enrolled0ConditionsRheumatoid Arthritis, Myositis
NCT05906641 nacompletednot on this mapstarted 2023, after this paper: background citation

Modulation of Secondary Bile Acids Through the Intestinal Microbiota After Consumption of a High-protein Diet.

TypeinterventionalSponsorInstituto Nacional de Ciencias Medicas y Nutricion Salvador ZubiranRan2023 to 2023Enrolled22ConditionsHealthyArmsHigh-protein diet
3 · Its place in the literature

Who cites it

1,355 citing papers in PubMed, 8 syntheses or guidelines pooled it, 2,532 citations in OpenAlex.

  1. Pooled it
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  3. Exposome Risk Factors for Vitiligo: A Systematic Evidence Review.American journal of clinical dermatology · 2026
    Pooled it
  4. Global Microbiome: Core and Unique Signatures Across Diverse Populations.International journal of molecular sciences · 2026
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1,295 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Rasnik K SinghUniversity of California, Los Angeles, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA.
Hsin-Wen ChangDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USA.
Di YanDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USA.
Kristina M LeeDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USA.
Derya UcmakDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USA.
Kirsten WongDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USA.
Michael AbroukUniversity of California, Irvine, School of Medicine, Irvine, CA, 92697, USA.
Benjamin FarahnikUniversity of Vermont College of Medicine, Burlington, VT, 05405, USA.
Mio NakamuraDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USA.
Tian Hao ZhuUniversity of Southern California Keck School of Medicine, Los Angeles, CA, 90033, USA.
Tina BhutaniDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USA.
Wilson LiaoDepartment of Dermatology, University of California, San Francisco, 2340 Sutter St. Room N431, Box 0808, San Francisco, CA, 94115, USA. wilson.liao@ucsf.edu.ORCID 0000-0001-7883-6439
University of California, San Francisco · USUniversity of California, Irvine · USUniversity of California, Los Angeles · USUniversity of Southern California · USUniversity of Vermont · US

Funding

MHC and KIR Region Genomics in PsoriasisU01AI119125 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LIAO, WILSON · 2015 to 2019
$3.5M
Identification of Causal Variants in PsoriasisR01AR065174 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LIAO, WILSON · 2013 to 2016
$1.8M
NIAID NIH HHS U01 AI119125NIAMS NIH HHS R01 AR065174
6 · The paper itself

Abstract

Recent studies have suggested that the intestinal microbiome plays an important role in modulating risk of several chronic diseases, including inflammatory bowel disease, obesity, type 2 diabetes, cardiovascular disease, and cancer. At the same time, it is now understood that diet plays a significant role in shaping the microbiome, with experiments showing that dietary alterations can induce large, temporary microbial shifts within 24 h. Given this association, there may be significant therapeutic utility in altering microbial composition through diet. This review systematically evaluates current data regarding the effects of several common dietary components on intestinal microbiota. We show that consumption of particular types of food produces predictable shifts in existing host bacterial genera. Furthermore, the identity of these bacteria affects host immune and metabolic parameters, with broad implications for human health. Familiarity with these associations will be of tremendous use to the practitioner as well as the patient.

Indexed as

DietGastrointestinal MicrobiomeHealthHumansPolyphenolsProbioticsPolyphenolsDietHealthMetabolismMicrobiomeMicrobiotaNutrition

Identifiers

PMID28388917
PMCPMC5385025
OpenAlexW2605052214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.