Evidence map›Paper›PMID 28387820›Full record

ArticleNucleic acids research2017

GalaxyHomomer: a web server for protein homo-oligomer structure prediction from a monomer sequence or structure.

Minkyung Baek, Taeyong Park, Lim Heo, Chiwook Park, Chaok Seok

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 141 citations in OpenAlex.

  1. Article
  2. When can AlphaFold predict the oligomeric states of proteins?Protein science : a publication of the Protein Society · 2026
    Article
  3. Article
  4. Topical mycophenolate for the treatment of uveitis-associated inflammation.Journal of ophthalmic inflammation and infection · 2026
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  5. Article
  6. Repurposing approved drugs targetingFrontiers in cellular and infection microbiology · 2026
    Article
  7. The Study of Ice-Binding Protein Oligomeric Complexes.International journal of molecular sciences · 2025
    Article
  8. Article
  9. Article
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  13. Article
  14. Review
  15. Article
  16. Article
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  18. Article
  19. Frontiers in cellular and infection microbiology · 2024
    Article
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Minkyung BaekDepartment of Chemistry, Seoul National University, Seoul 151-747, Korea.
Taeyong ParkDepartment of Chemistry, Seoul National University, Seoul 151-747, Korea.
Lim HeoDepartment of Chemistry, Seoul National University, Seoul 151-747, Korea.
Chiwook ParkDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
Chaok SeokDepartment of Chemistry, Seoul National University, Seoul 151-747, Korea.
Seoul National University · KRPurdue University West Lafayette · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Homo-oligomerization of proteins is abundant in nature, and is often intimately related with the physiological functions of proteins, such as in metabolism, signal transduction or immunity. Information on the homo-oligomer structure is therefore important to obtain a molecular-level understanding of protein functions and their regulation. Currently available web servers predict protein homo-oligomer structures either by template-based modeling using homo-oligomer templates selected from the protein structure database or by ab initio docking of monomer structures resolved by experiment or predicted by computation. The GalaxyHomomer server, freely accessible at http://galaxy.seoklab.org/homomer, carries out template-based modeling, ab initio docking or both depending on the availability of proper oligomer templates. It also incorporates recently developed model refinement methods that can consistently improve model quality. Moreover, the server provides additional options that can be chosen by the user depending on the availability of information on the monomer structure, oligomeric state and locations of unreliable/flexible loops or termini. The performance of the server was better than or comparable to that of other available methods when tested on benchmark sets and in a recent CASP performed in a blind fashion.

Indexed as

Models, StatisticalMolecular Docking SimulationProtein MultimerizationSoftwareAmino Acid SequenceBenchmarkingDatabases, ProteinHumansInternetMolecular Dynamics SimulationProteinsProtein Structure, SecondaryProteins

Identifiers

PMID28387820
PMCPMC5570155
OpenAlexW2605158478

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.