Evidence map›Paper›PMID 28386807›Full record

ReviewInfection2017

Acute human herpes virus 7 (HHV-7) encephalitis in an immunocompetent adult patient: a case report and review of literature.

Nicoletta Riva, Iacopo Franconi, Marianna Meschiari, Erica Franceschini, Cinzia Puzzolante, Gianluca Cuomo, Alessandro Bianchi, Francesca Cavalleri, Maurilio Genovese, Cristina Mussini

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  12. Herpesvirus-Associated Encephalitis: an Update.Current tropical medicine reports · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nicoletta RivaDepartment of Infectious Diseases, University of Modena and Reggio Emilia, via largo del Pozzo 71, 41123, Modena, Italy. nicoletta.riva@studio.unibo.it.ORCID http://orcid.org/0000-0002-4951-0787
Iacopo FranconiDepartment of Infectious Diseases, University of Modena and Reggio Emilia, via largo del Pozzo 71, 41123, Modena, Italy.
Marianna MeschiariDepartment of Infectious Diseases, University of Modena and Reggio Emilia, via largo del Pozzo 71, 41123, Modena, Italy.
Erica FranceschiniDepartment of Infectious Diseases, University of Modena and Reggio Emilia, via largo del Pozzo 71, 41123, Modena, Italy.
Cinzia PuzzolanteDepartment of Infectious Diseases, University of Modena and Reggio Emilia, via largo del Pozzo 71, 41123, Modena, Italy.
Gianluca CuomoDepartment of Infectious Diseases, University of Modena and Reggio Emilia, via largo del Pozzo 71, 41123, Modena, Italy.
Alessandro BianchiDepartment of Infectious Diseases, University of Modena and Reggio Emilia, via largo del Pozzo 71, 41123, Modena, Italy.
Francesca CavalleriNeuroradiology Unit, Department of Neuroscience, Nuovo Ospedale Civile S. Agostino Estense di Modena, Azienda Unità Sanitaria Locale di Modena, Modena, Italy.
Maurilio GenoveseNeuroradiology Unit, Department of Neuroscience, Nuovo Ospedale Civile S. Agostino Estense di Modena, Azienda Unità Sanitaria Locale di Modena, Modena, Italy.
Cristina MussiniDepartment of Infectious Diseases, University of Modena and Reggio Emilia, via largo del Pozzo 71, 41123, Modena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of an acute HHV-7 encephalitis involving the nucleus of the VI cranial nerve in an immunocompetent host. The patient was an adult male admitted to our Clinic with headache, diplopia, fever, nausea, vertigo, asthenia and general malaise. PCR for viral and bacterial genomes was run on both serum and cerebral spinal fluid (CSF) after performing lumbar puncture, resulting positive only for HHV-7 DNA on CSF. MRI showed hyperintensity in FLAIR signal in the dorsal pons, in the area of the VI cranial nerve nucleus. Empirical therapy with Acyclovir and Dexamethasone was started at the time of admission and was continued after the microbiology results. After three days of therapy diplopia, fever and other previous clinical manifestations improved and the patient recovered normal sight. Our case report contributes to a better understanding of the presentation, diagnosis and treatment of HHV-7 encephalitis in immunocompetent patients due to reactivation in adult age.

Indexed as

AcyclovirAdultAnti-Inflammatory AgentsAntiviral AgentsDexamethasoneDiagnosis, DifferentialEncephalitisHerpesvirus 7, HumanHumansImmunocompetenceMaleRadiculopathyRoseolovirus InfectionsTreatment OutcomeAcyclovirAnti-Inflammatory AgentsAntiviral AgentsDexamethasoneDiplopiaEncephalitisHHV-7Immunocompetent host

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.