ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2017
Predictors of the course of quality of life during therapy in women with primary breast cancer.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- A Systematic Review of Health-Related Quality of Life in Women with HER2-Positive Metastatic Breast Cancer Treated with Trastuzumab.PharmacoEconomics - open · 2024Pooled it
- Health-related quality of life in Asian patients with breast cancer: a systematic review.BMJ open · 2018Pooled it
- 12-Month Trajectories of Health-Related Quality of Life Following Hospitalization in German Cancer Centers-A Secondary Data Analysis.Current oncology (Toronto, Ont.) · 2024Article
- Awareness, offer, and use of psychosocial services by breast cancer survivors in Germany: a prospective multi-centre study.Archives of gynecology and obstetrics · 2023Article
- Association of social service counseling in breast cancer patients with financial problems, role functioning and employment-results from the prospective multicenter BRENDA II study.Archives of gynecology and obstetrics · 2023Article
- Article
- Trajectories of quality of life in breast cancer survivors during the first year after treatment: a longitudinal study.BMC women's health · 2023Article
- Associations of Molecular-Genetic Bioenergetics and Chemotherapy-Induced Fatigue Symptoms in Patients with Breast Cancer: A proposal development.Nursing & healthcare international journal · 2023Article
- Quality of Life and Sexual Satisfaction in Women with Breast Cancer Undergoing a Surgical Treatment and in Their Male Partners.Journal of clinical medicine · 2022Article
- EORTC QLQ-C30 general population normative data for Italy by sex, age and health condition: an analysis of 1,036 individuals.BMC public health · 2022Article
- Long-term improvement of quality of life in patients with breast cancer: supporting patient-physician communication by an electronic tool for inpatient and outpatient care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- How is quality of life defined and assessed in published research?Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Review
- Predictors for Fear of Cancer Recurrence in Breast Cancer Patients Referred to Radiation Therapy During the COVID-19 Pandemic: A Multi-Center Cross-Section Survey.Frontiers in oncology · 2021Article
- Impact of Time to Initiation of Treatment on the Quality of Life of Women with Breast Cancer.International journal of environmental research and public health · 2020Article
- Factors influencing quality of life of Asian breast cancer patients and their caregivers at diagnosis: perceived medical and psychosocial needs.Singapore medical journal · 2020Observational
- Quality of Life of Women with Breast Cancer and Socio-Demographic Factors.Asian Pacific journal of cancer prevention : APJCP · 2020Article
- PROMs following breast-conserving therapy for breast cancer: results from a prospective longitudinal monocentric study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Article
- Association Between Inflammatory Biomarker C-Reactive Protein and Radiotherapy-Induced Early Adverse Skin Reactions in a Multiracial/Ethnic Breast Cancer Population.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2018Article
- Prevalence of physical problems detected by the distress thermometer and problem list in patients with breast cancer.Psycho-oncology · 2018Article
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMultimodal therapies affect the quality of life (QoL) of patients with primary breast cancer (PBC). The objectives of this prospective study were to explore the changes in QoL from diagnosis to conclusion of adjuvant therapy and to identify predictive factors of QoL.
methodsBefore surgery (t1), before onset of adjuvant treatment (t2) and after completion of adjuvant chemo- or radiotherapy (t3), patients with PBC (n = 759) completed the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire, Charlson Comorbidity Index, Patient Health Questionnaire and Perceived Involvement in Care Scales. Predictors of the course of global QoL were estimated using multinomial logistic regression. Effect estimates are odds ratios (OR) and their 95% confidence intervals (CIs).
resultsGlobal QoL improved between t1 and t3, while physical functioning, emotional functioning and fatigue deteriorated. QoL before surgery was more often poor in patients <60 years (OR 2.2, 95% CI 1.5-3.1) and in those with comorbid mental illnesses (OR 8.6, CI 5.4-13.7). Forty-seven percentage reported good global QoL both at t1 and at t3. QoL improved in 28%, worsened in 10% and remained poor in 15%. Compared to patients with consistently good global QoL, a course of improving QoL was more often seen in patients who had received a mastectomy and in those with intense fear of treatment before surgery. A course of decreasing QoL was more often found in patients who were treated with chemotherapy. QoL stayed poor in patients with chemotherapy, mastectomy and intense fear. There was no evidence that radiotherapy, progressive disease or perceived involvement impact the course of QoL.
conclusionsYounger age and comorbid mental illnesses are associated with poor QoL pre-therapeutically. QoL is more likely to stay or become poor in patients who receive chemotherapy.
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