Evidence map›Paper›PMID 28386655›Full record

ArticleClinical and experimental nephrology2018

Impact of low-density lipoprotein cholesterol on decline in estimated glomerular filtration rate in apparently healthy young to middle-aged working men.

Akihiro Kuma, Bungo Uchino, Yoko Ochiai, Masatoshi Kawashima, Kazuhiko Enta, Masahito Tamura, Yutaka Otsuji, Akihiko Kato

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical and experimental nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Akihiro KumaSecond Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi, Kitakyushu, 807-8555, Japan. akihiro_k@me.com.
Bungo UchinoHealth Promotion Center, Yamaha Motor Co., Ltd., 2500 Shingai, Iwata, 438-8501, Japan.
Yoko OchiaiHealth Promotion Center, Yamaha Motor Co., Ltd., 2500 Shingai, Iwata, 438-8501, Japan.
Masatoshi KawashimaHealth Care Center, Central Japan Railway Company, 68 Kurogane, Aoi, Shizuoka, 420-0851, Japan.
Kazuhiko EntaHealth Care Center, Central Japan Railway Company, 68 Kurogane, Aoi, Shizuoka, 420-0851, Japan.
Masahito TamuraKidney Center, University Hospital of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi, Kitakyushu, 807-8556, Japan.
Yutaka OtsujiSecond Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi, Kitakyushu, 807-8555, Japan.
Akihiko KatoBlood Purification Unit, Hamamatsu University Hospital, 1-20-1 Handayama, Higashi, Hamamatsu, 431-3125, Japan.
University of Occupational and Environmental Health Japan · JPCentral Japan Railway (Japan) · JPYamaha (Japan) · JPHamamatsu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt remains to be fully clarified whether there is a relationship between uncontrolled dyslipidemia and decline in estimated glomerular filtration rate (eGFR) in the general population. Therefore, this study's aim was to test the association of dyslipidemia with changes in eGFR in apparently healthy working men.

methodsWe retrospectively examined the annual medical check-up list of 14,510 male workers aged 20-60 years with eGFR ≥ 60 mL/min/1.73 m

resultsMean age and eGFR were 38.5 years and 82.3 mL/min/1.73 m

conclusionIncreased LDL-C levels are associated with the development of incident CKD and eGFR decline in young to middle-aged working men without hypertension and/or DM.

Indexed as

Glomerular Filtration RateAdultCholesterol, LDLDyslipidemiasHumansJapanMaleMiddle AgedOccupational HealthReference ValuesRenal Insufficiency, ChronicRetrospective StudiesRisk FactorsYoung AdultCholesterol, LDLChronic kidney diseaseDyslipidemiaHealth check-upMetabolic syndromeOccupational health

Identifiers

PMID28386655
OpenAlexW2604760398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.