Evidence map›Paper›PMID 28386594›Full record

ReviewACS central science2017

Nanotechnology-Driven Therapeutic Interventions in Wound Healing: Potential Uses and Applications.

Suzana Hamdan, Irena Pastar, Stefan Drakulich, Emre Dikici, Marjana Tomic-Canic, Sapna Deo, Sylvia Daunert

Abstract readReview
In one paragraph

Review in ACS central science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

130 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Investigating the Wound Healing Potential of CuCOBiological trace element research · 2026
    Article
  5. Review
  6. Lipid Microspheres for Topical Delivery of Norfloxacin: Development and Evaluation.Recent advances in drug delivery and formulation · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
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  16. Article
  17. Review
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  20. Article

70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Suzana HamdanDepartment of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami , 1011 NW 15th Street, Miami, Florida 33136, United States.
Irena PastarWound Healing and Regenerative Medicine Research Program, Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami , 1011 NW 15th Street, Miami, Florida 33136, United States.
Stefan DrakulichWound Healing and Regenerative Medicine Research Program, Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami , 1011 NW 15th Street, Miami, Florida 33136, United States.
Emre DikiciDepartment of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami , 1011 NW 15th Street, Miami, Florida 33136, United States.
Marjana Tomic-CanicWound Healing and Regenerative Medicine Research Program, Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami , 1011 NW 15th Street, Miami, Florida 33136, United States.
Sapna DeoDepartment of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami , 1011 NW 15th Street, Miami, Florida 33136, United States.
Sylvia DaunertDepartment of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami , 1011 NW 15th Street, Miami, Florida 33136, United States.

Funding

PHOTOPROTEINS AS LABELS IN BIOLUMINESCENCE ASSAYSR01GM047915 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI DAUNERT, SYLVIA · 2000 to 2013
$3.5M
Perforin-2: The role of a novel antimicrobial protein in diabetic foot ulcersR01NR015649 · NINR · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI STRBO, NATASA, TOMIC-CANIC, MARJANA · 2015 to 2019
$2.6M
iPSC-derived Repair-Responsive Fibroblasts to Heal Diabetic Foot UlcersR01DK098055 · NIDDK · TUFTS UNIVERSITY BOSTON · PI GARLICK, JONATHAN A · 2012 to 2015
$2.6M
Micro-RNA Molecules as Regulators of Diabetic Wound HealingR01NR013881 · NINR · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI TOMIC-CANIC, MARJANA · 2012 to 2015
$1.7M
Sensitive Detection of Viral Persistency Using Bioluminescent Stem-Loop ProbesR01GM114321 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI DEO, SAPNA K · 2015 to 2019
$1.5M
Development of the Cellular Biomarker for Diabetic Foot UlcersRC1DK086364 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BREM, HAROLD, TOMIC-CANIC, MARJANA · 2009 to 2010
$903k
Nanocarrier-targeted mesenchymal stem cells to treat inflammatory bowel diseaseR21AI124058 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ABREU, MARIA TERESA, DAUNERT, SYLVIA · 2016 to 2017
$422k
NIAID NIH HHS R21 AI124058NIDDK NIH HHS R01 DK098055NIDDK NIH HHS RC1 DK086364NIGMS NIH HHS R01 GM047915NIGMS NIH HHS R01 GM114321NINR NIH HHS R01 NR013881NINR NIH HHS R01 NR015649
6 · The paper itself

Abstract

The chronic nature and associated complications of nonhealing wounds have led to the emergence of nanotechnology-based therapies that aim at facilitating the healing process and ultimately repairing the injured tissue. A number of engineered nanotechnologies have been proposed demonstrating unique properties and multiple functions that address specific problems associated with wound repair mechanisms. In this outlook, we highlight the most recently developed nanotechnology-based therapeutic agents and assess the viability and efficacy of each treatment, with emphasis on chronic cutaneous wounds. Herein we explore the unmet needs and future directions of current technologies, while discussing promising strategies that can advance the wound-healing field.

Identifiers

PMID28386594
PMCPMC5364456

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.