Evidence map›Paper›PMID 28386573›Full record

ArticleNeurophotonics2017

Spatial landscape of oxygen in and around microvasculature during epileptic events.

Cong Zhang, Mohammad Moeini, Frédéric Lesage

Open access · bronzeAbstract read
In one paragraph

Article in Neurophotonics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Astrocytic endfoot CaJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Cong ZhangÉcole Polytechnique de Montréal, Department of Electrical Engineering, Montreal, Quebec, Canada; Montreal Heart Institute, Montreal, Quebec, Canada.
Mohammad MoeiniÉcole Polytechnique de Montréal, Department of Electrical Engineering, Montreal, Quebec, Canada; Montreal Heart Institute, Montreal, Quebec, Canada.
Frédéric LesageÉcole Polytechnique de Montréal, Department of Electrical Engineering, Montreal, Quebec, Canada; Montreal Heart Institute, Montreal, Quebec, Canada.
Montreal Heart Institute · CAPolytechnique Montréal · CA

Funding

Enabling widespread use of high resolution imaging of oxygen in the brainR24NS092986 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI BOAS, DAVID A, VINOGRADOV, SERGEI · 2015 to 2018
$1.2M
NINDS NIH HHS R24 NS092986
6 · The paper itself

Abstract

Measuring changes in cerebral oxygen in tissue microdomains during epilepsy is important to identify hypoxic potential. Here, using a custom-built two-photon microscopy system, we present microscopic measurements of oxygen partial pressure ([Formula: see text]) in cortical microvessels and tissue of anesthetized mice during 4-aminopyridine (4-AP)-induced epileptic seizures. Investigating epileptic events, we characterized the distribution of the "initial dip" in [Formula: see text] in arterioles, venules, and tissue near the 4-AP injection site. Our results reveal a correlation between the percent change in [Formula: see text] during the "initial dip" and the diameter of nearest arterioles and venules.

Indexed as

epilepsyoxygen partial pressuretwo-photon phosphorescence lifetime microscopy

Identifiers

PMID28386573
PMCPMC5350260
OpenAlexW2612186152

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.