Evidence map›Paper›PMID 28386270›Full record

ArticlePPAR research2017

Fimasartan Ameliorates Nonalcoholic Fatty Liver Disease through PPAR

Yong-Jik Lee, Yoo-Na Jang, Yoon-Mi Han, Hyun-Min Kim, Jong-Min Jeong, Hong Seog Seo

Open access · goldAbstract read
In one paragraph

Article in PPAR research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
  5. Article
  6. Article
  7. Evidence-based complementary and alternative medicine : eCAM · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yong-Jik LeeCardiovascular Center, Guro Hospital, Korea University, 80 Guro-dong, Guro-gu, Seoul 152-703, Republic of Korea.ORCID 0000-0001-8814-0099
Yoo-Na JangCardiovascular Center, Guro Hospital, Korea University, 80 Guro-dong, Guro-gu, Seoul 152-703, Republic of Korea.
Yoon-Mi HanCardiovascular Center, Guro Hospital, Korea University, 80 Guro-dong, Guro-gu, Seoul 152-703, Republic of Korea.
Hyun-Min KimCardiovascular Center, Guro Hospital, Korea University, 80 Guro-dong, Guro-gu, Seoul 152-703, Republic of Korea.
Jong-Min JeongCardiovascular Center, Guro Hospital, Korea University, 80 Guro-dong, Guro-gu, Seoul 152-703, Republic of Korea.
Hong Seog SeoCardiovascular Center, Guro Hospital, Korea University, 80 Guro-dong, Guro-gu, Seoul 152-703, Republic of Korea; The Korea University-Korea Institute of Science and Technology (KU-KIST) Graduate School of Converging Science and Technology, Seoul, Republic of Korea.ORCID 0000-0003-2346-0299
Korea University Medical Center · KRKorea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the effects of fimasartan on nonalcoholic fatty liver disease in hyperlipidemic and hypertensive conditions, the levels of biomarkers related to fatty acid metabolism were determined in HepG2 and differentiated 3T3-L1 cells treated by high fatty acid and liver and visceral fat tissue samples of spontaneously hypertensive rats (SHRs) given high-fat diet. In HepG2 cells and liver tissues, fimasartan was shown to increase the protein levels of peroxisome proliferator-activated receptor delta (PPAR

Identifiers

PMID28386270
PMCPMC5366769
OpenAlexW2596547617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.