Evidence map›Paper›PMID 28386239›Full record

ArticleFrontiers in physiology2017

Skeletal Muscle myomiR Are Differentially Expressed by Endurance Exercise Mode and Combined Essential Amino Acid and Carbohydrate Supplementation.

Lee M Margolis, Holly L McClung, Nancy E Murphy, Christopher T Carrigan, Stefan M Pasiakos

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01714479 (Skeletal Muscle and Physical Performance Responses to Leucine-Enriched Nutrition Supplementation During Load Carriage), which is not on this map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01714479 nacompletednot on this map

Skeletal Muscle and Physical Performance Responses to Leucine-Enriched Nutrition Supplementation During Load Carriage

TypeinterventionalSponsorUnited States Army Research Institute of Environmental MedicineRan2012 to 2013Enrolled40ConditionsMuscle Loss, Muscle Anabolism, Muscle PerformanceArmsLeucine-enriched nutritional supplement, Placebo
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Non-coding RNAs in exercise immunology: A systematic review.Journal of sport and health science · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lee M MargolisMilitary Nutrition Division, US Army Research Institute of Environmental MedicineNatick, MA, USA; Oak Ridge Institute for Science and EducationOak Ridge, TN, USA.
Holly L McClungMilitary Nutrition Division, US Army Research Institute of Environmental Medicine Natick, MA, USA.
Nancy E MurphyMilitary Nutrition Division, US Army Research Institute of Environmental Medicine Natick, MA, USA.
Christopher T CarriganMilitary Nutrition Division, US Army Research Institute of Environmental MedicineNatick, MA, USA; Oak Ridge Institute for Science and EducationOak Ridge, TN, USA.
Stefan M PasiakosMilitary Nutrition Division, US Army Research Institute of Environmental Medicine Natick, MA, USA.
U.S. Army Research Institute of Environmental Medicine · USOak Ridge Institute for Science and Education

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skeletal muscle microRNAs (myomiR) expression is modulated by exercise, however, the influence of endurance exercise mode, combined with essential amino acid and carbohydrate (EAA+CHO) supplementation are not well defined. This study determined the effects of weighted versus non-weighted endurance exercise, with or without EAA+CHO ingestion on myomiR expression and their association with muscle protein synthesis (MPS). Twenty five adults performed 90 min of metabolically-matched (2.2 VO

Indexed as

Aktcycle ergometryload carriagemyomiRrpS6

Identifiers

PMID28386239
PMCPMC5362638
OpenAlexW2601090207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.