Evidence map›Paper›PMID 28386209›Full record

ArticleEsophagus : official journal of the Japan Esophageal Society2017

Prediction of the invasion depth of superficial squamous cell carcinoma based on microvessel morphology: magnifying endoscopic classification of the Japan Esophageal Society.

Tsuneo Oyama, Haruhiro Inoue, Miwako Arima, Kumiko Momma, Tai Omori, Ryu Ishihara, Dai Hirasawa, Manabu Takeuchi, Akihisa Tomori, Kenichi Goda

Abstract read
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In one paragraph

Article in Esophagus : official journal of the Japan Esophageal Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 180 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
180citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

180 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  4. [Clinical Practice Guideline for Endoscopic Resection of Early Gastrointestinal Cancer].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2020
    Guideline
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  10. Early detection of gastrointestinal cancers in low- and middle-income countries: A risk-stratified framework and implementation roadmap.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Review
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  19. Reply to Gkegkes et al.Endoscopy international open · 2026
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120 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tsuneo OyamaDepartment of Endoscopy, Saku Central Hospital Advanced Care Center, Nagano, Japan.
Haruhiro InoueDigestive Disease Center, Showa University Koto Toyosu Hospital, Tokyo, Japan.
Miwako ArimaDepartment of Gastroenterology, Saitama Cancer Center, Saitama, Japan.
Kumiko MommaDepartment of Endoscopy, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo, Japan.
Tai OmoriCenter for Diagnostic and Therapeutic Endoscopy, Keio University, Tokyo, Japan.
Ryu IshiharaDepartment of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan.
Dai HirasawaDepartment of Gastroenterology, Sendai City Medical Center, Miyagi, Japan.
Manabu TakeuchiDepartment of Gastroenterology, Niigata University Medical and Dental Hospital, Niigata, Japan.
Akihisa TomoriDepartment of Gastroenterology, Saku Central Hospital Advanced Care Center, Nagano, Japan.
Kenichi GodaDepartment of Endoscopy, The Jikei University School of Medicine, 3-25-8 Nishi-shimbashi, Minato-ku, Tokyo, 105-8461 Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Predicting invasion depth of superficial esophageal squamous cell carcinoma is crucial in determining the precise indication for endoscopic resection because the rate of lymph node metastasis increases in proportion to the invasion depth of the carcinoma. Previous studies have shown a close relationship between microvascular patterns observed by Narrow Band Imaging magnifying endoscopy and invasion depth of the superficial carcinoma. Thus, the Japan Esophageal Society (JES) developed a simplified magnifying endoscopic classification for estimating invasion depth of superficial esophageal squamous cell carcinomas. We conducted a prospective study to evaluate the diagnostic values of type B vessels in the pretreatment estimation of invasion depth of superficial esophageal squamous cell carcinomas utilizing JES classification, the criteria of which are based on the degree of irregularity in the microvascular morphology. Type A microvessels corresponded to noncancerous lesions and lack severe irregularity; type B, to cancerous lesions, and exhibit severe irregularity. Type B vessels were subclassified into B1, B2, and B3, diagnostic criteria for T1a-EP or T1a-LPM, T1a-MM or T1b-SM1, and T1b-SM2 tumors, respectively. We enrolled 211 patients with superficial esophageal squamous cell carcinoma. The overall accuracy of type B microvessels in estimating tumor invasion depth was 90.5 %. We propose that the newly developed JES magnifying endoscopic classification is useful in estimating the invasion depth of superficial esophageal squamous cell carcinoma.

Indexed as

Esophageal cancerInvasion depthJapan esophageal society classificationMagnifying endoscopySquamous cell carcinoma

Identifiers

PMID28386209
PMCPMC5362661

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.